Fiber optic plasmon resonance sensor for recording action potential; A theoretically evaluated proposal

T. Tekieh, P. Sasanpour
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Abstract

A non destructive optical sensor for recording of neural cell activity has been proposed and its performance and sensitivity has been evaluated theoretically. The sensor structure is based on using surface Plasmon resonance utilizing optical fiber, where thin film of gold layer has been deposited on the surface of core structure. The performance of proposed method has been calculated theoretically using transfer matrix method. The results of analysis show that by selection of proper wavelength for operation, the optical intensity response of sensor will track the voltage pattern of action potential completely. The all optical response of sensor is applicable in recording the electrical activity without any electric contact and destruction of cells accordingly.
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记录动作电位的光纤等离子体共振传感器;经过理论评估的提案
提出了一种用于记录神经细胞活动的无损光学传感器,并对其性能和灵敏度进行了理论评价。该传感器结构基于利用光纤的表面等离子体共振,在芯结构表面沉积了一层金薄膜。利用传递矩阵法对该方法的性能进行了理论计算。分析结果表明,通过选择合适的工作波长,传感器的光强响应可以完全跟踪动作电位的电压模式。传感器的全光响应适用于记录电活动,没有任何电接触和破坏相应的细胞。
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