Biological properties of rare-earth doped bioactive glass

A. Baranowska, M. Kochanowicz, J. Zmojda, P. Miluski, A. Wajda, M. Leśniak, D. Dorosz
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引用次数: 5

Abstract

In the article, the effect of samarium ions doping on the spectroscopic and biological properties of 45S5 Bioglass® was presented. The luminescence spectra of doped glasses have been analyzed in the visible range under 405 nm laser excitation. The in vitro method for testing the apatite-forming ability of bioactive glasses was used. Crushed to 100μm fractions bioactive glasses were immersed in Simulated Body Fluid (SBF) prepared by the Kokubo method. The material was incubated at 37°C for 3 days and then the measurements of ions (Ca, Na, Si) release in SBF were carried out. The bioactivity test indicated that Sm3+ ions affect not only on the luminescent properties of the bioactive glasses but also their capability of creating the hydroxycarbonate-apatite (HCA) layer.
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稀土掺杂生物活性玻璃的生物学特性
本文研究了钐离子掺杂对45S5生物玻璃®光谱和生物学性能的影响。在405 nm激光激发下,分析了掺杂玻璃在可见光范围内的发光光谱。采用体外法测定生物活性玻璃形成磷灰石的能力。将粉碎至100μm的生物活性玻璃浸入Kokubo法制备的模拟体液中。37℃孵育3 d,测定SBF中Ca、Na、Si离子的释放量。生物活性试验表明,Sm3+离子不仅影响生物活性玻璃的发光性能,而且影响其形成羟基碳酸盐-磷灰石(HCA)层的能力。
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