Synchronous primary malignancy of ovary and cervix with different histopathology: a rare presentation

K. Srivastava, F. Zahra
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引用次数: 11

Abstract

Background: Synchronous primary malignancies of the female genital tract are uncommon. Synchronous ovarian and cervical malignancies with different histopathology are rarer still. Case: A 55-year-old woman with poor general condition presented with ascites and post-menopausal bleeding. She was diagnosed to have ovarian serous adenocarcinoma, clinical stage III and cervical squamous cell carcinoma, clinical stage III B. She deteriorated rapidly after a cycle of chemotherapy and expired after nineteen days. Conclusion: Synchronous genital malignancies cause more clinical problems as compared to singly occurring ones. Hence such cases tend to be detected at an earlier stage. However, the prognosis is determined not only by clinical staging but also by histological grade of the adenomatous component. Incidence of multiple synchronous malignancies may be expected to increase in view of increased life expectancy.
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卵巢及子宫颈同步原发恶性肿瘤之不同病理组织:罕见表现
背景:女性生殖道同步原发恶性肿瘤并不常见。具有不同组织病理学的卵巢和宫颈同步恶性肿瘤更为罕见。病例:一名55岁妇女,一般情况较差,表现为腹水和绝经后出血。经诊断为卵巢浆液性腺癌临床III期和宫颈鳞状细胞癌临床III期b期,经一个周期化疗后病情迅速恶化,19天后死亡。结论:与单发性恶性肿瘤相比,伴发性恶性肿瘤引起的临床问题较多。因此,这类病例往往在较早阶段被发现。然而,预后不仅取决于临床分期,还取决于腺瘤成分的组织学分级。鉴于预期寿命的增加,多种同步恶性肿瘤的发病率可能会增加。
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