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The Effects of Tofu Consumption on Menopause Symptoms and Equol Level (7-hydroxy-3-(4-hydroxyphenyl) chroman) 食用豆腐对更年期症状和雌马酚(7-羟基-3-(4-羟基苯基)铬的影响
Pub Date : 2018-12-01 DOI: 10.5005/jp-journals-10032-1152
F. Erfiandi, T. Madjid, M. Ritonga, H. Susanto, B. Handono, H. Susiarno
Background: Improvements in both health and welfare in Indonesia have increased the life expectancy, thus the number of women who experience menopause period would be increasing. Menopause symptoms resulting from estrogen deficiency often cause problems, such as menstrual cycle changes, hot flushes, dyspareunia, urethritis, incontinence, urgency, frequent micturition, insomnia, or sexual dysfunction. This symptoms happened since perimenopause age. Phytoestrogens and their metabolites, equol, binds to estrogen receptors and induce biological effects resembling estrogen. The most important content of phytoestrogens are isoflavones. Isoflavones could be found in foods or drinks that contain soya (soy beans), such as tofu. Equol, a bacterial metabolite and the only hormonally active daidzein metabolite, is a good predictor to determine the degree of menopause symptoms. Method: The study design was an experimental study with pre and post design. The aim of this study was to determine the effect of regular tofu consumption for three months on the symptoms of menopause and excreted human urinary equol level. Subjects were perimenopause women (n = 25) that were interviewed using questionnaire guidance of menopause rating scale (MRS). Urine samples were analyzed using high performance liquid chromatography (HPLC). Results: The result showed that regular tofu consumption significantly reduced menopause symptoms and equol level (p value <0.05). Conclusion: Research concluded there was decrease in the degree of menopause symptoms and increased equol level in perimenopause women after consuming tofu regularly for 3 months. This results can be an alternative choices beside hormonal drugs that we used regularly to decrease menopause symptoms.
背景:印度尼西亚健康和福利的改善提高了预期寿命,因此经历更年期的妇女人数将会增加。由雌激素缺乏引起的更年期症状经常引起问题,如月经周期改变、潮热、性交困难、尿道炎、尿失禁、尿急、尿频、失眠或性功能障碍。这些症状发生在围绝经期。植物雌激素及其代谢产物雌马酚与雌激素受体结合并诱导类似雌激素的生物效应。植物雌激素中最重要的成分是异黄酮。异黄酮可以在含有大豆(大豆)的食品或饮料中找到,比如豆腐。雌马酚是一种细菌代谢物,也是唯一具有激素活性的大豆苷元代谢物,是确定更年期症状程度的良好预测因子。方法:采用前后设计的实验研究。本研究的目的是确定三个月定期食用豆腐对更年期症状和排泄的人尿雌酚水平的影响。研究对象为围绝经期妇女(n = 25),采用更年期评定量表(MRS)指导问卷进行访谈。采用高效液相色谱法对尿样进行分析。结果:经常食用豆腐可显著降低绝经期症状和雌酚水平(p值<0.05)。结论:研究表明,围绝经期妇女定期食用豆腐3个月后,更年期症状程度有所减轻,雌酮水平有所升高。这个结果可以作为我们常用的减少更年期症状的激素药物之外的另一种选择。
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引用次数: 0
VBAC In Women Undergoing IOL With Dinoprostone Versus Spontaneous Labor 人工晶状体植入迪诺前列酮与自然分娩妇女的VBAC
Pub Date : 2015-10-08 DOI: 10.5580/IJGO.28478
J. Alves, C. Vilhena, C. Tomás, I. Antunes, J. Metello, Isabel Natário, Marco Puga, E. Casal
OBJECTIVE: To compare the rate of vaginal birth in women attempting vaginal birth after caesarean delivery (VBAC) through labour induction with dinoprostone versus a trial of spontaneous labour. METHODS: A 10-year retrospective cohort study in a tertiary care hospital of women with one prior caesarean delivery. Women who attempted VBAC with labour induction with dinoprostone were compared with women undergoing spontaneous labour. Logistic regression analyses were performed to assess the relationship between VBAC success and labour induction taking into account confounding variables. Both maternal and neonatal safety were studied to find a difference between the group with spontaneous labour versus the group labour induction. RESULTS: A total of 1076 women in the cohort attempted VBAC (649 with spontaneous labour and 427 with induced labour). Women who were given a trial of spontaneous labour were more likely to have a successful VBAC (70.3% compared with 48.7%, odds ratio (OR) 2.49, 95% confidence interval (CI) 1.93–3.21). If women have had a previous vaginal delivery they were more likely to have a successful VBAC, OR of 2.98, 95% CI 2.08-4.27. The risk of uterine rupture (0.5% for induced labour compared with 0.6% for spontaneous labour) or overall morbidity (2.7% compared with 2.1%) was not significantly increased in the women with labour induction. CONCLUSION: Women with a previous caesarean section have a lower VBAC rate with labour induction versus spontaneous labour. If they have a previous vaginal delivery, the chance of a vaginal delivery increases. Overall, vaginal birth is safe and effective in women with one caesarean section with labour induction with dinoprostone.
目的:比较使用迪诺前列素引产的剖腹产(VBAC)后阴道分娩的妇女与自然分娩的妇女的阴道分娩率。方法:在一家三级医院对有一次剖腹产史的妇女进行10年回顾性队列研究。用迪诺前列酮引产尝试VBAC的妇女与自然分娩的妇女进行比较。考虑混杂变量,进行逻辑回归分析以评估VBAC成功与引产之间的关系。研究了产妇和新生儿的安全性,以发现自然分娩组与引产组之间的差异。结果:队列中共有1076名妇女尝试VBAC(649名自然分娩,427名引产)。接受自然分娩试验的妇女更有可能成功进行VBAC(70.3%比48.7%,优势比(OR) 2.49, 95%可信区间(CI) 1.93-3.21)。如果女性以前有过阴道分娩经历,她们更有可能成功进行VBAC, OR为2.98,95% CI为2.08-4.27。引产组子宫破裂的风险(引产组为0.5%,自然分娩组为0.6%)或总发病率(2.7%,自然分娩组为2.1%)在引产组中没有显著增加。结论:有过剖宫产史的妇女引产与自然分娩的VBAC率较低。如果她们以前有过阴道分娩,阴道分娩的机会就会增加。总的来说,阴道分娩是安全有效的妇女一次剖腹产与迪诺前列酮引产。
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引用次数: 0
Female Genital Mutilation: Awareness And Attitude Of Nursing And Midwifery Students In Afikpo, Nigeria. 女性外阴残割:尼日利亚阿菲克波护理和助产学学生的意识和态度。
Pub Date : 2012-07-16 DOI: 10.5580/2c1b
E. Dike, E. Ojiyi, A. Chukwulebe, V. Egwuatu
OBJECTIVE: To determine the awareness and attitude of female Nursing and Midwifery students in Afikpo, Southeastern Nigeria towards female genital mutilation (FGM). METHOD; Information was obtained from 269 students of Schools of Nursing and Midwifery, Afikpo on their on their age, marital status, feelings about their circumcision status, problems associated with circumcision, who carried out the procedure and the accruedbenefitsfrom the procedure and attitude towards female genital mutilaton through a semi-structured questionnaire administered by researchers. RESULT; Out of the 269 respondents whose questionnaires were analyzed. The mean age of the respondents was 25.3 with 87.4% belonging to the 15-29 years range. The prevalence rate of FGM in the study group was 54.3%, while 82.9% of the uncircumcised group were happy about their status, 49.3% of the circumcised group expressed happiness over their status. For the circumcised group, 41.7% expressed feeling of unhappiness and only 5.7% of the uncircumcised group expressed unhappiness. The feeling expressed by the 2 groups is statistically significant (X 2 = 41.98; p< 0.005). Most of the respondents were aware of the complications of FGM with 86.2%, 83.35 and 75.85 identifying bleeding, transmission of HIV and painful coitus as complications respectively. Fifty one point 3 percent (51.3%) were of the view that FM curtails promiscuity, 7.5% of the circumcised group reported sexual difficulty as a complication of circumcision. All the respondents were of the legislation banning FGM and would not want their daughters circumcised. CONCLUSION: There is need to further raise the awareness of FGM and its associated harmful effects among women through health education and women socio-economic empowerment.
目的:了解尼日利亚东南部Afikpo地区护理和助产学专业女生对女性生殖器切割(FGM)的认知和态度。方法;通过研究人员进行的半结构化问卷调查,从Afikpo护理和助产学院的269名学生那里获得了关于他们的年龄、婚姻状况、对包皮环切术状况的感受、与包皮环切术相关的问题、谁进行了手术、从手术中获得的收益以及对切割女性生殖器官的态度的信息。结果;在269名调查对象中,受访者的平均年龄为25.3岁,其中87.4%为15-29岁。研究组女性外阴残割患病率为54.3%,未割包皮组中有82.9%的人对自己的现状感到满意,割包皮组中有49.3%的人对自己的现状表示满意。割包皮组41.7%的人表示不快乐,而未割包皮组只有5.7%的人表示不快乐。两组患者情感表达差异有统计学意义(x2 = 41.98;p < 0.005)。大多数调查对象知道女性生殖器切割的并发症,86.2%、83.35%和75.85%的人分别认为出血、艾滋病毒传播和性交疼痛是并发症。51.3%(51.3%)的人认为FM减少了滥交,7.5%的包皮环切组报告性困难是包皮环切术的并发症。所有的回答者都赞成立法禁止女性生殖器切割,并且不希望自己的女儿接受割礼。结论:需要通过健康教育和赋予妇女社会经济权力,进一步提高妇女对女性生殖器切割及其相关有害影响的认识。
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引用次数: 7
Extracellular Vesicles – A New Frontier In Medical Research. Researchers Can Tap On This Area For Opportunities To Further Improve Clinical Care 细胞外囊泡——医学研究的新前沿。研究人员可以利用这一领域的机会进一步改善临床护理
Pub Date : 2012-07-16 DOI: 10.5580/2bf1
K. Tan, S. Lim
The human genome, proteome and microbiome have been extensively studied for the last two decades. One area which was less studied and perhaps neglected by scientists has been in an area related to cell secretions. Extracellular vesicles (EV) have now become the next focus of intensive scientific research. They comprise an assortment of extracellular structures, separately or variously known as exosomes, lipid membrane vesicles, microvesicles, microparticles, nanoparticles, ectosomes and apoptotic bodies. This emerging field pertains to nano & microparticles that carry proteins and RNA, both of which serve important cellular functions, and is likely to be an important player in the fast evolving field of nanomedicine. EVs are secreted by many cell types and are present in many bodily fluids (plasma, saliva, urine, tear, milk, semen etc). Their levels and composition are altered in various diseases and hence are potential biomarkers. 1 They are an ideal source for biomarker discovery in plasma. Being encapsulated in lipid vesicles and easily extractable, this reduce the susceptibility of putative biomarkers to degradation during transport and storage, and enable biomarkers to be discovered without the confounding presence of high abundance plasma proteins e.g. albumin andimmunoglobulins. 2 They are intimately involved in cell signalling and therefore are fundamental to our understanding of biology and pathology. They were
在过去的二十年里,人类基因组、蛋白质组和微生物组得到了广泛的研究。一个研究较少,可能被科学家忽视的领域是与细胞分泌物有关的领域。细胞外囊泡(EV)已成为当前科学研究的下一个热点。它们包括各种各样的细胞外结构,分别被称为外泌体、脂膜囊泡、微囊泡、微粒、纳米粒子、外泌体和凋亡小体。这一新兴领域涉及携带蛋白质和RNA的纳米和微粒,它们都具有重要的细胞功能,并且可能成为快速发展的纳米医学领域的重要参与者。ev由许多细胞类型分泌,存在于许多体液中(血浆、唾液、尿液、眼泪、牛奶、精液等)。它们的水平和组成在各种疾病中发生改变,因此是潜在的生物标志物。它们是发现血浆中生物标志物的理想来源。由于被包裹在脂质囊泡中,易于提取,这降低了假定的生物标志物在运输和储存过程中对降解的敏感性,并使生物标志物能够在不存在高丰度血浆蛋白(如白蛋白和免疫球蛋白)的情况下被发现。它们与细胞信号传导密切相关,因此是我们理解生物学和病理学的基础。他们是
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引用次数: 0
Abdominal Colposacropexy With Permanent Polypropylen Mesh 用永久聚丙烯网片固定术
Pub Date : 2012-07-16 DOI: 10.5580/2c19
J. Ivović, D. Kljakić, S. Raičević
Introduction: Colposacropexy presents the gold standard for the treatment of vaginal prolapse. The incidence for vaginal vault prolapse is about 15% of women who underwent hysterectomy due to uterine prolapse, and in about 1% of women who had any other reasons for hysterectomy.The aim of the study: We describe here our experience with abdominal colposacropexy in the treatment of the vaginal vault prolapse occurring after hysterectomy with and without urinary stress incontinence.Material and methods: From 1999 to 2009 we treated 15 women with vaginal vault prolapse occurring due to hysterectomy. Our procedure included the use of non-absorbable permanent polypropylen mash by abdominal approach. The women treated with colposacropexy using polipropilen mesh by abdominal approach reported satisfactory improvement of quality of life, no recurrent vaginal prolapse, urinary stress incontinence, no dyspareunia, no bowel dysfunction.Results: Follow up was between 9 months and 10 years (3.7 years). All patients reported satisfactory results with significant improvement of quality of life. There was no recurrence of the prolapse, no de nuovo urinary stress incontinence or dyspareunia.Conclusions : Abdominal sacrocolpopexy with permanent mesh is a safe and effective treatment of the vaginal vault prolapse after hysterectomy. INTRODUCTION & OBJECTIVES Vaginal vault prolapse is a rare event after hysterectomy, affecting quality of life by its local physical effects (pressure, bulging, heaviness or discomfort) or its effect on urinary, bowel or sexual function. Urinary symptoms include both symptoms related to incontinence or urinary retention (incomplete emptying), bowel symptoms include constipation or faecal incontinence, and symptoms of sexual dysfunction include dyspareunia (pain during intercourse) or avoiding intercourse due to embarrassment.(1) Vaginal vault prolapse is mostly a preventable complication of hysterectomy. Adequate suspension of the vaginal apex after hysterectomy with use of shortened cardinal and uterosacral ligaments will draw the proximal vagina over the levator plate. This results in support for the distal vagina. The essence of surgical repair of vaginal vault prolapse is to create a new suspension with the same vaginal support. Transvaginal sacrospinous fixation and transabdominal sacrocolpo-suspension accomplish this.(2) The goal of this work is to reveal cure of the vaginal vault prolapse after hysterectomy with polypropylene non – absorbable permanent mesh, Prolene monofilament (totally macroporous). We describe here our experience with abdominal colposacropexy in the treatment of the vaginal vault prolapse occurring after hysterectomy with and without urinary stress incontinence. MATERIAL AND METHODS From 1999 to 2010 fifteen colposacropexy were performed at women with extended vaginal vault prolapse (mean age 58 years). In all of these patients a hysterectomy was performed many years ago. Vaginal vault prolapse outside of the in
引言:阴道悬垂术是治疗阴道脱垂的金标准。阴道穹窿脱垂的发生率在因子宫脱垂而行子宫切除术的妇女中约为15%,在因其他原因行子宫切除术的妇女中约为1%。研究的目的:我们在这里描述了我们在子宫切除术后阴道穹窿脱垂治疗伴有或不伴有尿压力性失禁的经验。材料与方法:从1999年到2009年,我们治疗了15例因子宫切除术而导致阴道穹窿脱垂的妇女。我们的手术包括使用不可吸收的永久性聚丙烯浆料经腹部入路。经腹部入路使用聚丙烯网片进行阴道固定术的妇女报告了令人满意的生活质量改善,无复发性阴道脱垂,尿压力性失禁,无性交困难,无肠功能障碍。结果:随访9个月~ 10年(3.7年)。所有患者均报告满意的结果,生活质量显著改善。无脱垂复发,无新发尿压力性失禁或性交困难。结论:永久性补片腹骶colpop固定术治疗子宫切除术后阴道穹窿脱垂安全有效。阴道拱顶脱垂是子宫切除术后罕见的事件,通过其局部物理效应(压力,肿胀,沉重或不适)或其对尿,肠或性功能的影响影响生活质量。泌尿系统症状包括与尿失禁或尿潴留(排空不全)相关的症状,肠道症状包括便秘或大便失禁,性功能障碍症状包括性交困难(性交时疼痛)或因尴尬而避免性交。(1)阴道拱顶脱垂大多是子宫切除术后可预防的并发症。子宫切除术后使用缩短的枢机韧带和子宫骶韧带适当悬挂阴道顶点,将阴道近端拉到提肛板上方。这导致了对阴道远端的支持。手术修复阴道穹窿脱垂的本质是创造一个具有相同阴道支撑的新悬架。经阴道骶棘固定术和经腹部骶骶悬吊术实现了这一目的。(2)本研究的目的是揭示聚丙烯不可吸收永久补片、聚丙烯单丝(全大孔)治疗子宫切除术后阴道穹窿脱垂的疗效。我们在这里描述我们的经验,腹腔阴道缩窄术治疗阴道穹窿脱垂发生在子宫切除术后,有或没有尿压力性失禁。材料与方法1999年至2010年,对15例阴道拱顶外伸性脱垂的女性(平均年龄58岁)进行了阴道悬垂术。所有这些病人都在多年前做过子宫切除术。所有患者均有阴道开口外的阴道穹窿脱垂和膀胱肠直肠膨出,并伴咳嗽显著增大。阴道黏膜呈热状,凹凸不平,有时出血。9名妇女术前未出现尿失禁。6名妇女出现尿失禁。在这6例中,我们采用经闭锁入路,用中尿道吊带进行了腹部阴道固定术。伴有盆腔器官脱垂的阴道穹窿脱垂分期分类——国际禁尿学会设计的量化系统(表1)。图1表1:阴道穹窿脱垂的分类III期有7名女性阴道穹窿脱垂至膜环以下,8名女性阴道完全外翻(图1)。图2图1术前外观图3图2阴道壁后腹所有患者需用力排尿,6例需排水,1例残余尿150cm。随访时对患者进行膀胱、肠道和性症状的访谈。盆腔检查及残尿量测定。记录围手术期并发症及任何中间手术。所有患者均采用经腹入路,11例患者采用Pfannenstiel切口(因为子宫切除术采用同一切口),4例患者采用内侧开腹术。阴道两侧伸展(图2)。回到mm.提肛肌(图3),并向前到膀胱颈,在那里触摸气囊导管(图4)。腹腔阴道固定术使用永久性聚丙烯网3/ 6图4图3 -直肠阴道间隙图5图4 -膀胱阴道间隙放置聚丙烯网,沿阴道壁固定,mm.提肛肌用可吸收缝线3/0固定。 每根缝合线首先穿过补片的后叶,深深穿过阴道后壁的纤维肌肉厚度,然后在同一点从补片中取出。将缝合线放置在距阴道顶点远端1至2厘米和3至4厘米的横线上。在阴道顶端,我们为网片的后叶缝1 -3针。骶骨前峰上方在中筋膜右侧打开腹膜(图5),用一针不可吸收的3/0针固定前峰网(图6)。图7图6覆盖腹膜的网状物闭合在聚丙烯移植物上方(图6)。术后阴道壁内收(图7)。图8图7术后外观围手术期未见严重并发症。24小时后引流。患者3天后出院。结果平均随访3.7年,范围9个月- 10年,复发性阴道脱垂1例(6.6%),无排异移植物,无残尿,无肠功能障碍。无患者因阴道粘连而出现性问题。性行为在手术后没有改变。5例术前性行为不活跃的患者术后没有恢复性行为。所有患者均无排尿问题。在术前压力性尿失禁患者中,经尿道入路置入无张力尿道中带后成功率为83.3%。其中一名妇女在手术后没有改善。
{"title":"Abdominal Colposacropexy With Permanent Polypropylen Mesh","authors":"J. Ivović, D. Kljakić, S. Raičević","doi":"10.5580/2c19","DOIUrl":"https://doi.org/10.5580/2c19","url":null,"abstract":"Introduction: Colposacropexy presents the gold standard for the treatment of vaginal prolapse. The incidence for vaginal vault prolapse is about 15% of women who underwent hysterectomy due to uterine prolapse, and in about 1% of women who had any other reasons for hysterectomy.The aim of the study: We describe here our experience with abdominal colposacropexy in the treatment of the vaginal vault prolapse occurring after hysterectomy with and without urinary stress incontinence.Material and methods: From 1999 to 2009 we treated 15 women with vaginal vault prolapse occurring due to hysterectomy. Our procedure included the use of non-absorbable permanent polypropylen mash by abdominal approach. The women treated with colposacropexy using polipropilen mesh by abdominal approach reported satisfactory improvement of quality of life, no recurrent vaginal prolapse, urinary stress incontinence, no dyspareunia, no bowel dysfunction.Results: Follow up was between 9 months and 10 years (3.7 years). All patients reported satisfactory results with significant improvement of quality of life. There was no recurrence of the prolapse, no de nuovo urinary stress incontinence or dyspareunia.Conclusions : Abdominal sacrocolpopexy with permanent mesh is a safe and effective treatment of the vaginal vault prolapse after hysterectomy. INTRODUCTION & OBJECTIVES Vaginal vault prolapse is a rare event after hysterectomy, affecting quality of life by its local physical effects (pressure, bulging, heaviness or discomfort) or its effect on urinary, bowel or sexual function. Urinary symptoms include both symptoms related to incontinence or urinary retention (incomplete emptying), bowel symptoms include constipation or faecal incontinence, and symptoms of sexual dysfunction include dyspareunia (pain during intercourse) or avoiding intercourse due to embarrassment.(1) Vaginal vault prolapse is mostly a preventable complication of hysterectomy. Adequate suspension of the vaginal apex after hysterectomy with use of shortened cardinal and uterosacral ligaments will draw the proximal vagina over the levator plate. This results in support for the distal vagina. The essence of surgical repair of vaginal vault prolapse is to create a new suspension with the same vaginal support. Transvaginal sacrospinous fixation and transabdominal sacrocolpo-suspension accomplish this.(2) The goal of this work is to reveal cure of the vaginal vault prolapse after hysterectomy with polypropylene non – absorbable permanent mesh, Prolene monofilament (totally macroporous). We describe here our experience with abdominal colposacropexy in the treatment of the vaginal vault prolapse occurring after hysterectomy with and without urinary stress incontinence. MATERIAL AND METHODS From 1999 to 2010 fifteen colposacropexy were performed at women with extended vaginal vault prolapse (mean age 58 years). In all of these patients a hysterectomy was performed many years ago. Vaginal vault prolapse outside of the in","PeriodicalId":158103,"journal":{"name":"The Internet journal of gynecology and obstetrics","volume":"366 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123192997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Influence Of Genital Tract Symptomatology On Genital Human Papilloma Virus 生殖道症状学对生殖道人乳头瘤病毒的影响
Pub Date : 2012-07-16 DOI: 10.5580/2c1c
Emmanuel Ojiyi Emeka, I. D. Ephraim, Chinwendu Anolue Fredrick, O. Chijioke, A. Okechukwu, Ngadda Hamibu
Aim: To study the association between genital tract symptomatology and human papilloma virus (HPV) of the cervix.Method: The subjects were 450 randomly selected sexually active women attending the antenatal, postnatal, gynaecology and family planning clinics in the Department of Obstetrics and Gynaecology of the University of Maiduguri Teaching Hospital, Nigeria between April 2001 and May 2002. The Pap smear of these patients were examined microscopically for evidence of HPV Infection. Questionnaires assessing various genital tract symptomatology of the patients were administered.Result: Abnormal smears occurred in 245 (54.5%) of the patients screened. Forty eight women (10.7%) had HPV associated changes constituting 19.6% of all abnormal smears. Their ages ranged between 15 and 64 years, with a mean of 26±3 years. There was a statistically significant association between abnormal vaginal discharge, irregular menstruation, postmenopausal and postcoital bleeding and genital HPV infection. Conclusion: Women with abnormal vaginal discharge, irregular menstruation, postmenopausal and postcoital bleeding are at increased risk of acquiring infection of the cervix and should be the target in a sporadic or an organized cervical cancer screening programme without discriminating other sexually active women.
目的:探讨宫颈人乳头瘤病毒(HPV)与生殖道症状的关系。方法:研究对象是随机选择的450名2001年4月至2002年5月期间在尼日利亚迈杜古里大学教学医院妇产科产前、产后、妇科和计划生育门诊就诊的性活跃妇女。这些患者的子宫颈抹片检查显微镜下HPV感染的证据。对患者的各种生殖道症状进行问卷评估。结果:筛查患者涂片异常245例(54.5%)。48名妇女(10.7%)有HPV相关改变,占所有异常涂片的19.6%。年龄15 ~ 64岁,平均26±3岁。阴道分泌物异常、月经不调、绝经后和性交后出血与生殖器HPV感染有统计学意义。结论:阴道分泌物异常、月经不规律、绝经后和性交后出血的妇女子宫颈感染的风险增加,应作为零星或有组织的宫颈癌筛查计划的目标,而不歧视其他性活跃妇女。
{"title":"The Influence Of Genital Tract Symptomatology On Genital Human Papilloma Virus","authors":"Emmanuel Ojiyi Emeka, I. D. Ephraim, Chinwendu Anolue Fredrick, O. Chijioke, A. Okechukwu, Ngadda Hamibu","doi":"10.5580/2c1c","DOIUrl":"https://doi.org/10.5580/2c1c","url":null,"abstract":"Aim: To study the association between genital tract symptomatology and human papilloma virus (HPV) of the cervix.Method: The subjects were 450 randomly selected sexually active women attending the antenatal, postnatal, gynaecology and family planning clinics in the Department of Obstetrics and Gynaecology of the University of Maiduguri Teaching Hospital, Nigeria between April 2001 and May 2002. The Pap smear of these patients were examined microscopically for evidence of HPV Infection. Questionnaires assessing various genital tract symptomatology of the patients were administered.Result: Abnormal smears occurred in 245 (54.5%) of the patients screened. Forty eight women (10.7%) had HPV associated changes constituting 19.6% of all abnormal smears. Their ages ranged between 15 and 64 years, with a mean of 26±3 years. There was a statistically significant association between abnormal vaginal discharge, irregular menstruation, postmenopausal and postcoital bleeding and genital HPV infection. Conclusion: Women with abnormal vaginal discharge, irregular menstruation, postmenopausal and postcoital bleeding are at increased risk of acquiring infection of the cervix and should be the target in a sporadic or an organized cervical cancer screening programme without discriminating other sexually active women.","PeriodicalId":158103,"journal":{"name":"The Internet journal of gynecology and obstetrics","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128869005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe Intraabdominal Trauma In Illegal Abortion: A Case Report 非法流产所致严重腹内创伤1例
Pub Date : 2012-07-16 DOI: 10.5580/2c40
Gautam N. Gole, U. Santpur, R. Kaul
Unsafe abortion represents a preventable yet major cause for maternal mortality in India. A majority of these abortions are performed confidentially. Complications occur in a large portion of these cases and ultimately require tertiary care. Intestinal perforation is a rare complication of induced abortion but it is not rare in our country. It is most commonly seen in countries where abortions are performed by people with sharp pointed instruments, without proper training and knowledge of anatomy. Bowel perforation occurs when the posterior vaginal wall or uterus is violated, allowing the instrument to pierce the underlying structures. Here we discuss case of a woman who sustained injury to small bowel with a long mesenteric tear, rectal transection and tear of the urinary bladder.
不安全堕胎是印度孕产妇死亡的一个可预防的主要原因。大多数堕胎都是秘密进行的。这些病例中大部分发生并发症,最终需要三级护理。肠道穿孔是人工流产的一种罕见并发症,但在我国并不罕见。这在一些国家最为常见,在这些国家,堕胎是由使用尖锐器械的人进行的,没有经过适当的培训,也没有解剖学知识。当阴道后壁或子宫被侵犯时,就会发生肠穿孔,使器械能够穿透下面的结构。在这里我们讨论的情况下,一个妇女谁持续损伤小肠长肠系膜撕裂,直肠横断和膀胱撕裂。
{"title":"Severe Intraabdominal Trauma In Illegal Abortion: A Case Report","authors":"Gautam N. Gole, U. Santpur, R. Kaul","doi":"10.5580/2c40","DOIUrl":"https://doi.org/10.5580/2c40","url":null,"abstract":"Unsafe abortion represents a preventable yet major cause for maternal mortality in India. A majority of these abortions are performed confidentially. Complications occur in a large portion of these cases and ultimately require tertiary care. Intestinal perforation is a rare complication of induced abortion but it is not rare in our country. It is most commonly seen in countries where abortions are performed by people with sharp pointed instruments, without proper training and knowledge of anatomy. Bowel perforation occurs when the posterior vaginal wall or uterus is violated, allowing the instrument to pierce the underlying structures. Here we discuss case of a woman who sustained injury to small bowel with a long mesenteric tear, rectal transection and tear of the urinary bladder.","PeriodicalId":158103,"journal":{"name":"The Internet journal of gynecology and obstetrics","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116668633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Placental Site Trophoblastic Tumor: A Case Report. 胎盘部位滋养细胞瘤1例报告。
Pub Date : 2012-07-16 DOI: 10.5580/2c84
S. Samal, P. Pallavee, P. Sabita
A placental site trophoblastic tumour is a rare form of gestational trophoblastic neoplasia with a reported incidence of 1-2 % of all trophoblastic tumours. They have a varied clinical spectrum and usually present with irregular vaginal bleeding or amenorrhoea. They are commonly seen in reproductive age group and can occur after normal pregnancy, abortion or following gestational trophoblastic disease. Surgery is the mainstay of treatment. We present a case which was retrospectively diagnosed as placental site trophoblastic tumour following hysterectomy for abnormal uterine bleeding.
胎盘部位滋养细胞肿瘤是一种罕见的妊娠滋养细胞瘤,据报道发病率为所有滋养细胞肿瘤的1- 2%。他们有不同的临床谱,通常表现为不规则阴道出血或闭经。常见于育龄人群,可发生在正常妊娠、流产后或妊娠滋养细胞疾病后。手术是治疗的主要手段。我们报告一例因子宫异常出血而行子宫切除术后被回顾性诊断为胎盘部位滋养细胞瘤。
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引用次数: 7
Obstetric Outcomes In Premature Rupture Of The Membrane (Prom) 膜早破(Prom)的产科结局
Pub Date : 2012-05-21 DOI: 10.5580/2ecb
M. Gandhi, F. H. Shah, Chirag Panchal
There were 384 cases of PROM giving incidence of 5.2%. The incidence of PROM was higher in case of rural, young, primigravida patients. PROM more commonly occurred after 37 weeks and majority of patients delivered vaginally. The indications for LSCS were mainly fetal distress and non progressive first stage. Patients were managed aggressively and 355 (92.5%) of them were delivered within 24 hours. Maternal morbidity was 3.12% and maternal mortality was 0.26%. Neonatal morbidity was 3.38% and neonatal mortality was 2.86%. The majority of neonatal deaths occurred in preterm infants and newborns with low birth weight. CONCLUSIONS: PROM was associated with low birth weight and prematurity and thus led to high perinatal mortality. Maternal and neonatal morbidity were also increased. A proposed plan of "Aggressive management" irrespective of term of gestation is final answer to decrease maternal and neonatal morbidity and mortality.
胎膜早破384例,发生率5.2%。早膜早破的发生率在农村、年轻、初迁患者中较高。早PROM多发生在37周后,大多数患者是顺产。LSCS的适应症主要是胎儿窘迫和非进展性第一阶段。患者得到积极治疗,355例(92.5%)患者在24小时内分娩。产妇发病率为3.12%,死亡率为0.26%。新生儿发病率3.38%,新生儿死亡率2.86%。大多数新生儿死亡发生在早产儿和低出生体重新生儿中。结论:胎膜早破与低出生体重和早产有关,从而导致高围产期死亡率。产妇和新生儿的发病率也增加了。无论妊娠期如何,“积极管理”计划是降低孕产妇和新生儿发病率和死亡率的最终答案。
{"title":"Obstetric Outcomes In Premature Rupture Of The Membrane (Prom)","authors":"M. Gandhi, F. H. Shah, Chirag Panchal","doi":"10.5580/2ecb","DOIUrl":"https://doi.org/10.5580/2ecb","url":null,"abstract":"There were 384 cases of PROM giving incidence of 5.2%. The incidence of PROM was higher in case of rural, young, primigravida patients. PROM more commonly occurred after 37 weeks and majority of patients delivered vaginally. The indications for LSCS were mainly fetal distress and non progressive first stage. Patients were managed aggressively and 355 (92.5%) of them were delivered within 24 hours. Maternal morbidity was 3.12% and maternal mortality was 0.26%. Neonatal morbidity was 3.38% and neonatal mortality was 2.86%. The majority of neonatal deaths occurred in preterm infants and newborns with low birth weight. CONCLUSIONS: PROM was associated with low birth weight and prematurity and thus led to high perinatal mortality. Maternal and neonatal morbidity were also increased. A proposed plan of \"Aggressive management\" irrespective of term of gestation is final answer to decrease maternal and neonatal morbidity and mortality.","PeriodicalId":158103,"journal":{"name":"The Internet journal of gynecology and obstetrics","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126249126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
The Prevalence And Predictors Of Human Papilloma Virus Infection Of The Cervix At A University Teaching Hospital In Northern Nigeria. 尼日利亚北部一所大学教学医院宫颈乳头状瘤病毒感染的流行及预测因素
Pub Date : 2012-05-21 DOI: 10.5580/2eda
E. Ojiyi, C. Okeudo, E. Dike, F. Anolue, U. Onyeka, B. Audu, H. Ngadda
Introduction: The purpose of this study is to determine the prevalence and predictors of HumanPapilloma Virus (HPV) Infection of the cervix.Method: The subjects were 450 randomly selected sexually active women attending the antenatal,postnatal, gynaecology and family planning clinics in the Department of Obstetrics and Gynaecologyof the University of Maiduguri Teaching Hospital, Nigeria between April 2001 to May 2002. The PapSmear of these patients were examined microscopically for evidence of HPV Infection. Aquestionnaire assessing various socio-demographic characteristics of the patients were administered.Result: The prevalence rate of HPV was 10.7%. The peak age-specific prevalence of 11.7%occurred in the 15-19 years age group. There were significant associations between the occurrence ofHPV and multiple sexual partners, coital frequency, multiparity, contraceptive use, and marital status,Low socio-economic status abnormal vaginal discharge, irregular menstruation, postcoital andpostmenopausal bleeding.Conclusion: It is recommended that all sexually active women including teenagers should bescreened for cervical Human Papilloma Virus infection in organized systematic programme equippedwith a good call and recall system. There is therefore a need to move emphasis from the currentpractice of opportunistic screening to a systematic screening of the whole population at risk despitecost implications.
前言:本研究的目的是确定宫颈人乳头瘤病毒(HPV)感染的患病率和预测因素。方法:选取2001年4月至2002年5月在尼日利亚迈杜古里大学教学医院妇产科产前、产后、妇科和计划生育门诊就诊的450名性活跃妇女为研究对象。这些患者的PapSmear显微镜检查HPV感染的证据。对患者进行问卷调查,评估各种社会人口统计学特征。结果:HPV患病率为10.7%。15-19岁年龄组患病率最高,为11.7%。hpv的发生与多个性伴侣、性交频率、多胎、避孕措施的使用、婚姻状况、低社会经济地位、阴道分泌物异常、月经不调、性交后和绝经后出血有显著相关性。结论:建议对包括青少年在内的性活跃期妇女进行有组织有系统的宫颈人乳头瘤病毒感染筛查,并建立良好的报警和召回制度。因此,有必要将重点从目前的机会性筛查做法转移到对整个高危人群进行系统筛查,尽管这涉及成本问题。
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引用次数: 7
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The Internet journal of gynecology and obstetrics
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