CHARACTERISTICS OF ACUTE ISCHEMIC STROKE PATIENTS DUE TO SMALL VESSEL OCCLUSION

Richard Suherlim, Nyoman Angga Krishna Pramana, K. Tini, Ida Bagus Kusuma Putra, Ida Ayu Sri Indrayani
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Abstract

Background: Ischemic stroke account for about 87% of all stroke cases. This study will focus on ischemic stroke due to small vessel occlusion as one of the subtypes based on TOAST (trial of ORG 10172 in acute stroke treatment). Objective: To determine the characteristics of ischemic stroke patients caused by small vessel occlusion and are expected to be used as a basis for further research. Methods: A descriptive observational retrospective study regarding the characteristics of acute ischemic stroke patients due to small vessel occlusion at Sanglah Hospital. Secondary data were obtained from patient medical records. Results: The total number of cases of small vessel occlusion was 338. The majority of the sample were men (64.5%) between 40-60 years old (53.6%). Most of the samples were patients who had experienced an ischemic stroke for the first time (75.1%) with NIHSS (National Institute of Health Stroke Scale) scores showing mild (48.2%) and moderate (51.5%) symptoms. Around half of them had a history of hypertension (60.1%), dyslipidemia (59.5%), and diabetes mellitus (44.1%). The most common location of infarction was in the anterior circulation (77.5%) with almost the same ratio of right and left hemisphere locations. Conclusion: Ischemic stroke due to occlusion of small vessels at Sanglah Hospital Denpasar for 3 years was 35.2% of the total ischemic stroke cases. Half of the total sample had classic vascular risk factors. Further research is needed to determine another effective treatment strategy other than just secondary prevention such as life style moderation to prevent recurrency.
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小血管闭塞急性缺血性脑卒中患者的特点
背景:缺血性卒中约占卒中病例的87%。本研究将重点研究基于TOAST (ORG 10172在急性卒中治疗中的试验)的小血管闭塞缺血性卒中亚型之一。目的:了解缺血性脑卒中患者小血管闭塞的特点,为进一步研究奠定基础。方法:对桑格拉医院小血管闭塞急性缺血性脑卒中患者的特点进行描述性观察性回顾性研究。次要数据来自患者的医疗记录。结果:小血管闭塞338例。大多数样本是男性(64.5%),年龄在40-60岁之间(53.6%)。大多数样本为首次经历缺血性卒中的患者(75.1%),其NIHSS(国立卫生研究院卒中量表)评分为轻度(48.2%)和中度(51.5%)症状。约半数患者有高血压(60.1%)、血脂异常(59.5%)和糖尿病(44.1%)病史。最常见的梗死部位是前循环(77.5%),左右半球的发生率几乎相同。结论:登巴萨Sanglah医院3年内小血管闭塞性缺血性卒中占缺血性卒中总病例的35.2%。一半的样本有典型的血管危险因素。需要进一步的研究来确定除了二级预防之外的另一种有效的治疗策略,如生活方式调节以防止复发。
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