Plication of The Medial Patellofemoral Ligament for The Treatment of Chronic Patella Dislocations and Refractory Patellofemoral Syndrome. A Retrospective Case Series and Review

Victor Hoang, Ben Moyer, Mehdi Talle, C. Vanier, T. Watson, Randa A. Bascharon, Daniel Lee, Nick Liu
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The goal of this project was to evaluate the outcomes associated with MPFL plication. Study Design: Case Series; Level IV Methods: A retrospective analysis of patients with recurrent patella dislocations, Refractory Patellofemoral Syndrome (RPS) or Patellofemoral Pain Syndrome (PFPS) treated with plication of the MPFL between 2009 2018 with minimum four month follow up. The primary outcome variable was patient overall satisfaction, Visual Analogue Scale for Pain (VAS) and Kujala (Anterior Knee Pain) Score. Results: Seven patients met the inclusion criteria. Their demographic and pre-surgery details are in Table 1. A large majority of patients (85.7%) were satisfied, and VAS pain scale ratings were four or less. Only one of the seven patients was not satisfied (Table 2), and that individual also had the lowest Kujala score. The VAS pain scale and the Kujala score were not correlated (Spearman rank correlation, rho=-0.218, P=0.638; Figure 1), nor was there a clear relationship between time since surgery and Kujala score (rho=0.607, P=0.167; Figure 2). Conclusion: Plication of the MPFL has a high success in improving both Kujala (Anterior Knee Pain) Score and Visual Analogue Scale (VAS) as well as return to regular activities. We believe this is a safe and effective technique in improving chronic patella dislocations and Refractory Patellofemoral Syndrome with minimal perioperative morbidity. Introduction Patella Instability/ Patella Dislocation Patella instability and dislocation are not covered under the umbrella of RPS or PFPS, however it can be a source of anterior knee pain, especially in younger female patients ages 10-17 [1]. The average incidence of primary patellar dislocation is roughly 5.8 per 100,000 cases [1]. Causes of patella instability/subluxation and dislocation include trauma, general lateral ligamentous laxity, Citation: Hoang V, Moyer B, Talle M, Vanier C, Watson T, Bascharon, R, Lee, D, Liu, N (2019) Plication of The Medial Patellofemoral Ligament for The Treatment of Chronic Patella Dislocations and Refractory Patellofemoral Syndrome. A Retrospective Case Series and Review. Sports Injr Med 5: 155. DOI: 10.29011/25769596.100055 2 Volume 5; Issue 01 Sports Injr Med, an open access journal ISSN: 2576-9596 lateralized Q-angle, recurvatum, tibial external rotation, vastus medialis weakness, trochlear dysplasia, and/or genu valgum without displacement from the groove in subluxation and complete displacement in dislocation [2-4]. The excessive lateral tilt and glide in subluxation produces a redistribution of forces along the patellar articular surface causing pain and feelings of instability. Dislocations are also a source of pain and involve complete displacement, often laterally, but in rare cases can occur medially and superiorly [2,3,5,6]. Studies have shown that dislocations can lead to recurrent instability, decrease in activity, cartilage damage, fractures, and progression of osteoarthritis [1,7-10]. In the interest of pain relief, joint preservation, and restoration of biomechanics, either conservative or surgical intervention can be beneficial. Extensive long-term clinical study on conservative treatment of patellar dislocations is lacking. However, a study done by Maenpaa and Lehto found that immobilization of the knee in extension after a primary dislocation for six weeks reduced the risk of secondary dislocation three-fold compared to patients that were not [7]. This may provide enough of an opportunity for the MPFL to heal or other structures to tighten up prior to therapy, but more research is required in this area [3]. Patients with patellar instability and dislocations are at a higher risk of subsequent dislocations and even after conservative treatment, experience a 15-44% rate of recurrence [1,3,7]. These patients may benefit from surgical intervention. This, however, remains controversial. According to a review included in a study by Jain, et al. (2011), there is insufficient evidence to support immediate surgical stabilization of the patella after an initial dislocation, and only after a second dislocation should it be considered due to an increased risk of subsequent dislocations.3 In patients with lateral subluxations and repeat dislocations, the MPFL may be damaged or stretched and in need of repair. This procedure’s utilization has increased in recent years, and in spite of a noted complication rate of 26%, [11] a number of retrospective studies claim excellent outcomes from 80-96% of patients improving even when used to repair previously failed surgical interventions for instability [2,1215]. Refractory Patellofemoral Syndrome (RPS) or Patellofemoral Pain Syndrome (PFPS) Anterior knee pain has a high incidence affecting 22/1000 patients/year and accounts for 25-40% of knee pain visits in sports medicine clinics [16,17]. Pain originating from impaired patellar tracking as a result of tight lateral soft tissues with compression of the lateral facet against anterolateral femur and increased lateral patellar tilt is often classified as Refractory Patellofemoral Syndrome (RPS) or Patellofemoral Pain Syndrome (PFPS) [18]. The compression of the subchondral bone has been correlated to the pain, but pain can also be associated with the synovium, retinaculum, and associated neuromuscular structures [19]. Development of Refractory Patellofemoral Pain Syndrome is multifactorial. RPS has been often observed in active individuals and affects more women than men as a result of a widened Q-angle [17,20,21]. Other anatomical and biomechanical contributing factors include tight lateral retinaculum, tight IT band, foot pronation, externally rotated tibia, weak hip abductors and external rotators, weak vastus medialis, and injury to the extensor mechanism [8,21]. Weakness in the external rotators or abductors of the hip resulting in internal rotation of the femur, over eversion of the foot resulting in internal tibial rotation, or a combination of both may result in a functional or dynamic valgus deformity, also contributing to patellar maltracking [22]. Patients present with anterior knee pain from overuse, positive theatre sign (pain with activity after prolonged sitting), positive patellar compression test, and pain climbing/descending stairs [16,23-25]. Symptoms are exacerbated with flexion and can be recreated in the clinic utilizing a squat test. If hip abductor strength is in question, a single leg squat test can be utilized to identify hip muscle dysfunction [22]. Nonoperative Treatment of Refractory Patellofemoral Syndrome (RPS) or Patellofemoral Pain Syndrome (PFPS) Current treatments are centered on pain relief with eventual return to presymptomatic activity and improved patellar alignment. Treatment plans are evaluated on a per patient basis beginning with a focus on non-operative methods. Initially, patients are to avoid activities that cause pain (ie. running, high impact, stair running/ hill climbs) and are prescribed NSAID pain relievers. According to a meta-analysis of the Cochrane database of pharmacotherapy in the treatment of patellofemoral pain, one study showed use of Naproxen provided significant pain relief for 2-3 weeks, but was not significant in long term treatment. The same analysis found there is little evidence supporting the use of NSAIDS for reduction of knee pain in acute or chronic cases [26]. The analysis also explored the use of intra-articular corticosteroid injections and Glycosaminoglycan (GAG) derived viscosupplementation and it was determined that this form of treatment also lacks support from literature [26,27]. Over the course of five weeks, four test groups were compared, including one group consisting of GAGs with lidocaine injections, one group of two injections of saline and lidocaine, and no injections in two other groups participating in quadriceps strengthening physical therapy. The study found a significant difference in relief of symptoms between the GAGs with lidocaine versus the no injection group, but the injections failed to completely remedy patients’ symptoms which returned within six months [26,27]. Patellar Taping and Bracing A number of studies have found use of patellar taping and Citation: Hoang V, Moyer B, Talle M, Vanier C, Watson T, Bascharon, R, Lee, D, Liu, N (2019) Plication of The Medial Patellofemoral Ligament for The Treatment of Chronic Patella Dislocations and Refractory Patellofemoral Syndrome. A Retrospective Case Series and Review. Sports Injr Med 5: 155. DOI: 10.29011/25769596.100055 3 Volume 5; Issue 01 Sports Injr Med, an open access journal ISSN: 2576-9596 bracing reasonable when coupled with exercise therapy. Pfeiffer, et al. utilized tape in a medial direction and evaluated its ability to decrease lateral patellar displacement. The results were significant, but only before intense exercise, indicating that tape coupled with supervised, low intensity exercise therapy can be beneficial [28]. Two meta-analyses, one published in 2002 and another in 2008, also found that tape coupled with exercise provided significant improvement in reduction of pain compared to exercise alone. Sham tape also showed positive results, indicating that a placebo effect can also play a role in improvement of symptoms [29,30]. 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引用次数: 0

Abstract

Background: Anterior knee pain accounts for 25-40% of knee pain visits in sports medicine clinics. Refractory Patellofemoral Syndrome (RPS) and Chronic Patella Dislocations are often multifactorial but commonly the pain originates from impaired patellar tracking and increased lateral patellar tilt. The compression of the subchondral bone has been correlated to the pain as well as from the synovium, retinaculum, and associated neuromuscular structures. The plication of the Medial Patellofemoral Ligament (MPFL) counteracts these compressive and tilting forces improving symptoms of RPS and recurrent patella dislocations. The goal of this project was to evaluate the outcomes associated with MPFL plication. Study Design: Case Series; Level IV Methods: A retrospective analysis of patients with recurrent patella dislocations, Refractory Patellofemoral Syndrome (RPS) or Patellofemoral Pain Syndrome (PFPS) treated with plication of the MPFL between 2009 2018 with minimum four month follow up. The primary outcome variable was patient overall satisfaction, Visual Analogue Scale for Pain (VAS) and Kujala (Anterior Knee Pain) Score. Results: Seven patients met the inclusion criteria. Their demographic and pre-surgery details are in Table 1. A large majority of patients (85.7%) were satisfied, and VAS pain scale ratings were four or less. Only one of the seven patients was not satisfied (Table 2), and that individual also had the lowest Kujala score. The VAS pain scale and the Kujala score were not correlated (Spearman rank correlation, rho=-0.218, P=0.638; Figure 1), nor was there a clear relationship between time since surgery and Kujala score (rho=0.607, P=0.167; Figure 2). Conclusion: Plication of the MPFL has a high success in improving both Kujala (Anterior Knee Pain) Score and Visual Analogue Scale (VAS) as well as return to regular activities. We believe this is a safe and effective technique in improving chronic patella dislocations and Refractory Patellofemoral Syndrome with minimal perioperative morbidity. Introduction Patella Instability/ Patella Dislocation Patella instability and dislocation are not covered under the umbrella of RPS or PFPS, however it can be a source of anterior knee pain, especially in younger female patients ages 10-17 [1]. The average incidence of primary patellar dislocation is roughly 5.8 per 100,000 cases [1]. Causes of patella instability/subluxation and dislocation include trauma, general lateral ligamentous laxity, Citation: Hoang V, Moyer B, Talle M, Vanier C, Watson T, Bascharon, R, Lee, D, Liu, N (2019) Plication of The Medial Patellofemoral Ligament for The Treatment of Chronic Patella Dislocations and Refractory Patellofemoral Syndrome. A Retrospective Case Series and Review. Sports Injr Med 5: 155. DOI: 10.29011/25769596.100055 2 Volume 5; Issue 01 Sports Injr Med, an open access journal ISSN: 2576-9596 lateralized Q-angle, recurvatum, tibial external rotation, vastus medialis weakness, trochlear dysplasia, and/or genu valgum without displacement from the groove in subluxation and complete displacement in dislocation [2-4]. The excessive lateral tilt and glide in subluxation produces a redistribution of forces along the patellar articular surface causing pain and feelings of instability. Dislocations are also a source of pain and involve complete displacement, often laterally, but in rare cases can occur medially and superiorly [2,3,5,6]. Studies have shown that dislocations can lead to recurrent instability, decrease in activity, cartilage damage, fractures, and progression of osteoarthritis [1,7-10]. In the interest of pain relief, joint preservation, and restoration of biomechanics, either conservative or surgical intervention can be beneficial. Extensive long-term clinical study on conservative treatment of patellar dislocations is lacking. However, a study done by Maenpaa and Lehto found that immobilization of the knee in extension after a primary dislocation for six weeks reduced the risk of secondary dislocation three-fold compared to patients that were not [7]. This may provide enough of an opportunity for the MPFL to heal or other structures to tighten up prior to therapy, but more research is required in this area [3]. Patients with patellar instability and dislocations are at a higher risk of subsequent dislocations and even after conservative treatment, experience a 15-44% rate of recurrence [1,3,7]. These patients may benefit from surgical intervention. This, however, remains controversial. According to a review included in a study by Jain, et al. (2011), there is insufficient evidence to support immediate surgical stabilization of the patella after an initial dislocation, and only after a second dislocation should it be considered due to an increased risk of subsequent dislocations.3 In patients with lateral subluxations and repeat dislocations, the MPFL may be damaged or stretched and in need of repair. This procedure’s utilization has increased in recent years, and in spite of a noted complication rate of 26%, [11] a number of retrospective studies claim excellent outcomes from 80-96% of patients improving even when used to repair previously failed surgical interventions for instability [2,1215]. Refractory Patellofemoral Syndrome (RPS) or Patellofemoral Pain Syndrome (PFPS) Anterior knee pain has a high incidence affecting 22/1000 patients/year and accounts for 25-40% of knee pain visits in sports medicine clinics [16,17]. Pain originating from impaired patellar tracking as a result of tight lateral soft tissues with compression of the lateral facet against anterolateral femur and increased lateral patellar tilt is often classified as Refractory Patellofemoral Syndrome (RPS) or Patellofemoral Pain Syndrome (PFPS) [18]. The compression of the subchondral bone has been correlated to the pain, but pain can also be associated with the synovium, retinaculum, and associated neuromuscular structures [19]. Development of Refractory Patellofemoral Pain Syndrome is multifactorial. RPS has been often observed in active individuals and affects more women than men as a result of a widened Q-angle [17,20,21]. Other anatomical and biomechanical contributing factors include tight lateral retinaculum, tight IT band, foot pronation, externally rotated tibia, weak hip abductors and external rotators, weak vastus medialis, and injury to the extensor mechanism [8,21]. Weakness in the external rotators or abductors of the hip resulting in internal rotation of the femur, over eversion of the foot resulting in internal tibial rotation, or a combination of both may result in a functional or dynamic valgus deformity, also contributing to patellar maltracking [22]. Patients present with anterior knee pain from overuse, positive theatre sign (pain with activity after prolonged sitting), positive patellar compression test, and pain climbing/descending stairs [16,23-25]. Symptoms are exacerbated with flexion and can be recreated in the clinic utilizing a squat test. If hip abductor strength is in question, a single leg squat test can be utilized to identify hip muscle dysfunction [22]. Nonoperative Treatment of Refractory Patellofemoral Syndrome (RPS) or Patellofemoral Pain Syndrome (PFPS) Current treatments are centered on pain relief with eventual return to presymptomatic activity and improved patellar alignment. Treatment plans are evaluated on a per patient basis beginning with a focus on non-operative methods. Initially, patients are to avoid activities that cause pain (ie. running, high impact, stair running/ hill climbs) and are prescribed NSAID pain relievers. According to a meta-analysis of the Cochrane database of pharmacotherapy in the treatment of patellofemoral pain, one study showed use of Naproxen provided significant pain relief for 2-3 weeks, but was not significant in long term treatment. The same analysis found there is little evidence supporting the use of NSAIDS for reduction of knee pain in acute or chronic cases [26]. The analysis also explored the use of intra-articular corticosteroid injections and Glycosaminoglycan (GAG) derived viscosupplementation and it was determined that this form of treatment also lacks support from literature [26,27]. Over the course of five weeks, four test groups were compared, including one group consisting of GAGs with lidocaine injections, one group of two injections of saline and lidocaine, and no injections in two other groups participating in quadriceps strengthening physical therapy. The study found a significant difference in relief of symptoms between the GAGs with lidocaine versus the no injection group, but the injections failed to completely remedy patients’ symptoms which returned within six months [26,27]. Patellar Taping and Bracing A number of studies have found use of patellar taping and Citation: Hoang V, Moyer B, Talle M, Vanier C, Watson T, Bascharon, R, Lee, D, Liu, N (2019) Plication of The Medial Patellofemoral Ligament for The Treatment of Chronic Patella Dislocations and Refractory Patellofemoral Syndrome. A Retrospective Case Series and Review. Sports Injr Med 5: 155. DOI: 10.29011/25769596.100055 3 Volume 5; Issue 01 Sports Injr Med, an open access journal ISSN: 2576-9596 bracing reasonable when coupled with exercise therapy. Pfeiffer, et al. utilized tape in a medial direction and evaluated its ability to decrease lateral patellar displacement. The results were significant, but only before intense exercise, indicating that tape coupled with supervised, low intensity exercise therapy can be beneficial [28]. Two meta-analyses, one published in 2002 and another in 2008, also found that tape coupled with exercise provided significant improvement in reduction of pain compared to exercise alone. Sham tape also showed positive results, indicating that a placebo effect can also play a role in improvement of symptoms [29,30]. Unfortunately, the studies involved were focused on short-term results and the long-term effect
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髌股内侧韧带应用治疗慢性髌骨脱位及难治性髌股综合征。回顾性病例系列和回顾
背景:膝关节前侧疼痛占运动医学诊所膝关节疼痛就诊的25-40%。难治性髌股综合征(RPS)和慢性髌骨脱位通常是多因素的,但通常疼痛源于髌骨追踪受损和外侧髌骨倾斜增加。软骨下骨的压迫与疼痛以及滑膜、视网膜带和相关的神经肌肉结构有关。髌股内侧韧带(MPFL)的应用抵消了这些压缩和倾斜力,改善了RPS和复发性髌骨脱位的症状。这个项目的目的是评估与MPFL应用相关的结果。研究设计:案例系列;IV级方法:回顾性分析2009年至2018年期间接受MPFL应用治疗的复发性髌骨脱位,难治性髌骨综合征(RPS)或髌骨疼痛综合征(PFPS)患者,随访至少4个月。主要结局变量为患者总体满意度、疼痛视觉模拟量表(VAS)和Kujala(膝关节前侧疼痛)评分。结果:7例患者符合纳入标准。他们的人口统计和术前细节见表1。绝大多数患者(85.7%)满意,VAS疼痛评分在4分以下。7例患者中只有1例不满意(表2),且该患者的Kujala评分最低。VAS疼痛评分与Kujala评分不相关(Spearman秩相关,rho=-0.218, P=0.638;图1),术后时间与Kujala评分之间也没有明确的关系(rho=0.607, P=0.167;图2)结论:应用MPFL在改善Kujala(前膝关节疼痛)评分和视觉模拟评分(VAS)以及恢复正常活动方面取得了很高的成功。我们相信这是一种安全有效的技术,可改善慢性髌骨脱位和难治性髌骨股骨综合征,且围手术期发病率最低。髌骨不稳定/髌骨脱位髌骨不稳定和脱位不在RPS或PFPS的范围内,但它可能是膝关节前侧疼痛的一个来源,特别是在10-17岁的年轻女性患者中[1]。原发性髌骨脱位的平均发生率约为每10万例5.8例[1]。髌骨不稳定/半脱位和脱位的原因包括创伤,一般外侧韧带松弛,引用本文:Hoang V, Moyer B, Talle M, Vanier C, Watson T, Bascharon, R, Lee, D, Liu, N(2019)应用髌股内侧韧带治疗慢性髌骨脱位和难治性髌股综合征。回顾性病例系列和回顾。体育与医学杂志5:155。DOI: 10.29011/25769596.100055 2卷5;开放期刊《运动医学》第01期,ISSN: 2576-9596。半脱位时无槽移位、半脱位时无槽移位、胫骨外旋、股内侧肌无力、滑车发育不良和/或膝外翻[2-4]。半脱位时过度的侧向倾斜和滑动会使力量沿髌骨关节面重新分布,引起疼痛和不稳定感。脱位也是疼痛的一个来源,通常涉及外侧的完全移位,但在极少数情况下可发生内侧和上部[2,3,5,6]。研究表明,脱位可导致复发性不稳定、活动减少、软骨损伤、骨折和骨关节炎进展[1,7-10]。为了减轻疼痛,保护关节和恢复生物力学,保守或手术干预都是有益的。髌骨脱位保守治疗缺乏广泛的长期临床研究。然而,Maenpaa和Lehto的一项研究发现,与未固定的患者相比,原发性脱位后膝关节伸展固定6周可使继发性脱位的风险降低3倍[7]。这可能为MPFL在治疗前愈合或其他结构收紧提供了足够的机会,但这一领域还需要更多的研究[3]。髌骨不稳定和脱位的患者发生脱位的风险较高,即使经过保守治疗,复发率仍为15-44%[1,3,7]。这些患者可能受益于手术干预。然而,这仍然存在争议。根据Jain等人(2011)的一项研究综述,没有足够的证据支持在首次脱位后立即进行髌骨手术稳定,只有在第二次脱位后才应考虑手术稳定,因为后续脱位的风险增加在外侧半脱位和重复脱位的患者中,MPFL可能受损或拉伸,需要修复。 不幸的是,相关研究关注的是短期结果和长期影响
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