Treatment of retractile scar after a hypetrophic scar (HSs) in the hand with ADM (Dermacell)

Abstract

Hypertrophic scars can occur anywhere on skin after a skin injury or wound. The reason is not fully understood, the result is the abnormal production of extra collagen and a decrease in elastin, which lead to these undesirable thick, raised stiff scars. Sometimes surgery is performed to cut out the scar or redirect the lines of tension on the scar. Usually, surgery is considered when other treatment options have failed. Dermacell is human acellular matrix (hADM) that is intended for supplemental support and covering for soft tissue repair. It acts as ECM. The expression and proliferation of extracellular matrix (ECM) molecules in the dermis, mediated by a range of growth factors and cytokines, is a fundamental element of wound repair.