{"title":"Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies","authors":"Aditi Singh","doi":"10.5772/intechopen.84229","DOIUrl":null,"url":null,"abstract":"The clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/ gRNA system on the other hand, is a unique, targeted genome-modification technique derived from prokaryotic immune system. The cutting edge research and technology advancements in recent years have enabled the CRISPR-Cas9 system to become a popular tool for introducing heritable, precised, insertions and deletions in the eukaryotic genome.","PeriodicalId":336265,"journal":{"name":"Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies","volume":"38 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"26","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5772/intechopen.84229","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 26
Abstract
The clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/ gRNA system on the other hand, is a unique, targeted genome-modification technique derived from prokaryotic immune system. The cutting edge research and technology advancements in recent years have enabled the CRISPR-Cas9 system to become a popular tool for introducing heritable, precised, insertions and deletions in the eukaryotic genome.