Study of microelectronics for detecting and stimulating of central neural signals

Wang Zhigong, L. Xiaoying, Li Wenyuan, Wang Huiling, Zhang Zhenyu, Wang Yufeng, Cui Wei
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引用次数: 27

Abstract

Test circuits for the signal detection and the function electrical stimulation (FES) of neurons have been designed, implemented at first by using discrete devices and characterized off-body. The detecting circuit consisting of three-stage operational amplifiers has a controllable gain up to 10/sup 5/, a -3 dB bandwidth of 30 kHz, and an equivalent input noise of about 9 nV//spl radic/Hz. The FES circuit consisting of two-stage operational amplifiers has a bandwidth of more than 10 kHz and a variable gain from 20 dB to 60 dB can provide a current of more than 1 mA to a load of 10 k/spl Omega/ They are intended to connect with both cuff-type and staff-type microelectrodes. Integrated circuits (IC) for the neural signal process have been designed with features of low voltage and low power. A more biocompatible composite has been synthesized to modify the silicon and related material.
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中枢神经信号检测与刺激的微电子学研究
设计了用于神经元信号检测和功能电刺激(FES)的测试电路,最初采用离散器件实现,并进行了离体表征。由三级运算放大器组成的检测电路具有高达10/sup 5/的可控增益,-3 dB带宽为30 kHz,等效输入噪声约为9 nV//spl径向/Hz。FES电路由两级运算放大器组成,带宽超过10 kHz,增益从20 dB到60 dB不等,可以为10 k/spl ω /的负载提供超过1 mA的电流,它们旨在与cuff型和staff型微电极连接。设计了具有低电压、低功耗特点的神经信号处理集成电路。合成了一种更具有生物相容性的复合材料来修饰硅和相关材料。
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