PENGARUH VARIASI KONSENTRASI GELLING AGENT CARBOPOL 940 TERHADAP SIFAT FISIK SEDIAAN GEL HAND SANITIZER MINYAK ATSIRI DAUN KEMANGI (Ocimum Sanctum L.)

Iin Lidia Putama Mursal, Anggun Hari Kusumawati, Devi Hartianti Puspasari
{"title":"PENGARUH VARIASI KONSENTRASI GELLING AGENT CARBOPOL 940 TERHADAP SIFAT FISIK SEDIAAN GEL HAND SANITIZER MINYAK ATSIRI DAUN KEMANGI (Ocimum Sanctum L.)","authors":"Iin Lidia Putama Mursal, Anggun Hari Kusumawati, Devi Hartianti Puspasari","doi":"10.36805/farmasi.v4i1.617","DOIUrl":null,"url":null,"abstract":"ABSTRAK \nHand sanitizer adalah produk efektif dan murah yang dapat mengurangi mikroorganisme pada kulit. Banyak hand sanitizer yang mengandung etanol dan alkohol dengan kadar 60% -95% tetapi kandungan alkohol dalam hand sanitizer dapat menyebabkan resiko kesehatan. Penelitian ini bertujuan untuk melihat pengaruh gelling agent Carbopol 940 terhadap sifat fisik sediaan gel hand sanitizer. Konsentrasi yang digunakan untuk gelling agent Carbopol 940 yaitu 0,5%; 1%; 1,5%. Uji sifat fisik meliputi uji organoleptik, uji homogenitas, uji pH, uji viskositas, uji daya sebar dan uji daya lekat. Hasil penelitian sifat fisik sediaan gel hand sanitizer minyak atsiri daun kemangi yaitu peningkatan kadar gelling agent menyebabkan warna gel semakin pudar, wujud semakin kental, peningkatan viskositas, peningkatan daya lekat dan penurunan daya sebar. Berdasarkan uji sifat fisik sediaan gel hand sanitizer minyak atsiri daun kemangi dapat disimpulkan bahwa (F2) dengan konsentrasi 1% Carbopol 940 adalah formula optimal karena memenuhi semua persyaratan sifat fisik gel. \nKata kunci : gelling agent, carbopol 940, sifat fisik, Ocimum sanctum L. \n  \nABSTRACT \nHand sanitizers were effective and inexpensive product that can reduce of microorganims on the skin. Many hand sanitizer have contents up to 60%-95% ethanol and isopropyl alcohol, but using alcohol in hand sanitizer can cause health risks effect. The aim of this work was to determine the effects of gelling agent Carbopol 940 on physical properties of formulation gel hand sanitizer. The concentration that used for the Carbopol 940 gelling agent are 0,5%; 1%; 1,5%. The test of physical properties includes organoleptic, homogeneity, pH, viscosity, dispersive ability, and adhesion The results of this research on the physical properties gel hand sanitizer of basil essensial oil, showed that the increasing of gelling agent consentrasion, makes the gel getting faded, more thicker, increase of viscosity, adhesion and decrease of dispersive ability. Based on the physical properties test, (F2) with 1% concentration of Carbopol 940 is the optimal formula it caused by it suitable all the parameters of the physical properties of gel. \nKeywords : gelling agent, carbopol 940, physical properties, Ocimum sanctum L.","PeriodicalId":251083,"journal":{"name":"Pharma Xplore : Jurnal Ilmiah Farmasi","volume":"80 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"9","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharma Xplore : Jurnal Ilmiah Farmasi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36805/farmasi.v4i1.617","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 9

Abstract

ABSTRAK Hand sanitizer adalah produk efektif dan murah yang dapat mengurangi mikroorganisme pada kulit. Banyak hand sanitizer yang mengandung etanol dan alkohol dengan kadar 60% -95% tetapi kandungan alkohol dalam hand sanitizer dapat menyebabkan resiko kesehatan. Penelitian ini bertujuan untuk melihat pengaruh gelling agent Carbopol 940 terhadap sifat fisik sediaan gel hand sanitizer. Konsentrasi yang digunakan untuk gelling agent Carbopol 940 yaitu 0,5%; 1%; 1,5%. Uji sifat fisik meliputi uji organoleptik, uji homogenitas, uji pH, uji viskositas, uji daya sebar dan uji daya lekat. Hasil penelitian sifat fisik sediaan gel hand sanitizer minyak atsiri daun kemangi yaitu peningkatan kadar gelling agent menyebabkan warna gel semakin pudar, wujud semakin kental, peningkatan viskositas, peningkatan daya lekat dan penurunan daya sebar. Berdasarkan uji sifat fisik sediaan gel hand sanitizer minyak atsiri daun kemangi dapat disimpulkan bahwa (F2) dengan konsentrasi 1% Carbopol 940 adalah formula optimal karena memenuhi semua persyaratan sifat fisik gel. Kata kunci : gelling agent, carbopol 940, sifat fisik, Ocimum sanctum L.   ABSTRACT Hand sanitizers were effective and inexpensive product that can reduce of microorganims on the skin. Many hand sanitizer have contents up to 60%-95% ethanol and isopropyl alcohol, but using alcohol in hand sanitizer can cause health risks effect. The aim of this work was to determine the effects of gelling agent Carbopol 940 on physical properties of formulation gel hand sanitizer. The concentration that used for the Carbopol 940 gelling agent are 0,5%; 1%; 1,5%. The test of physical properties includes organoleptic, homogeneity, pH, viscosity, dispersive ability, and adhesion The results of this research on the physical properties gel hand sanitizer of basil essensial oil, showed that the increasing of gelling agent consentrasion, makes the gel getting faded, more thicker, increase of viscosity, adhesion and decrease of dispersive ability. Based on the physical properties test, (F2) with 1% concentration of Carbopol 940 is the optimal formula it caused by it suitable all the parameters of the physical properties of gel. Keywords : gelling agent, carbopol 940, physical properties, Ocimum sanctum L.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
抽象手疗养院是一种有效和廉价的产品,可以减少皮肤上的微生物。许多手疗养院含有60% -95%的乙醇和酒精,但疗养院的酒精含量可能会导致健康风险。本研究旨在探讨gelling agent Carbopol 940对hand sanitizer物理性能的影响。用于gelling agent Carbopol 940的浓度是0.5%;1%;1.5%。物理性能测试包括有机测试、同质测试、pH测试、粘性测试、舒适性测试和粘性测试。研究结果是,剂型hand sanitizer的生理本质是腐蚀性凝胶剂浓度的增加,导致凝胶褪色、粘性增加、粘性增加和sebar力的降低。根据剂型hand sanitizer的物理性质检测,可以得出结论(F2)百分之一的Carbopol 940的浓度是最理想的配方,因为它满足了凝胶的物理性质要求。关键字:gelling agent, carbopol 940,物理性质,眼动sanctum L。许多卫生工作者对乙醇和异丙醇的影响进行了60%-95%的控制,但使用医用酒精可以引起健康风险效应。这项工作的目标是确定gelling agent Carbopol 940关节卫生凝胶配方效果。用于Carbopol 940 gelling agent的集中是0.5%;1%;1.5%。体格测试》财产includes organoleptic homogeneity, pH值、viscosity dispersive不在乎,这和adhesion The results of research on之体格,财产凝胶手sanitizer罗勒essensial石油,那里那个gelling之increasing consentrasion探员,让《凝胶被faded更多thicker viscosity之增加,adhesion》和dispersive decrease不在乎。基于物理属性测试,(F2),百分之一的碳波率940是最完美的公式,由凝胶物理属性的参数提供。gelling agent, carbopol 940,物理性能,Ocimum sanctum L。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
ANALISIS HUBUNGAN SIKAP DAN PENGETAHUAN TERHADAP KEPATUHAN PENGGUNAAN Fe PADA IBU HAMIL DI PUSKESMAS KLARI SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN DARI EKSTRAK ETANOL BIJI KOPI ARABIKA (Coffea arabica) YANG TUMBUH DI DAERAH GAYO DENGAN METODE DPPH INSIDENSI TB PARU KASUS BARU PADA PASIEN DENGAN DM TIPE 2 DI SALAH SATU RUMAH SAKIT SWASTA CIKAMPEK FORMULASI, UJI STABILITAS FISIK DAN KOMPATIBILITAS PRODUK KOSMETIK ANTI-AGING DALAM SEDIAAN SERUM PUDDING HUBUNGAN KEPUASAN TERAPI DENGAN KUALITAS HIDUP PASIEN DIABETES MELLITUS TIPE-2 DI PELAYANAN PRIMER (PUSKESMAS JETIS 1 BANTUL)
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1