CARDIOVASCULAR RISK FACTORS AND PRESCRIPTION PATTERN AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS IN NORTH-EAST NIGERIA

Emmanuel AGADA DAVID, R. Soremekun, Y. M. Katagum, R. Aderemi-Williams
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Abstract

Cardiovascular disesaes are the leading cause of morbidity and mortality among diabetic patients. This study was a 12-months retrospective cross sectional audit of case folders of adult (>18 years) type 2 diabetic patients, who attended clinic at two (2) referral hospitals in North-East Nigeria, between June 2017 and May 2018. Patients’ data including socio-demographic characteristics, cardiovascular risk factors, medication history and clinical characteristics were retrieved. The data were presented as proportions and percentages in tables and pie chart formats. The analysis was done using statistical package for social sciences (SPSS) version 21.0. Of the 807 case folders that were reviewed, 64.5% were female patients, with majority (61.3%) below 50 yearsof age and 90.2% were married. Over 50% had secondary/primary education and most (57.9%) were unskilled labourers. About one-third (34.6%) were engaged in moderate to regular physical activities. The prevalence of hypertension, dyslipidaemia and obesity was 84.8%, 5.1% and 47.1% respectively. More than three quarters of the patients (87%) were on multiple oralantidiabetic agents and metformin was the most prescribed medication (93.8%). The antihypertensive agents with the highest prescription rate was lisinopril (57.9%), while 50.9%, 6.5%, and 2.7% received low dose acetylsalicylic acid, lipid lowering agents and pregabalin respectively. Hypertension was the most prevalent cardiovascular risk factor in the study population, followed by overweight/obesity. The prescription rate of metformin and Lisinopril is commendable, but there is need to increase the use of statins and pregabalin in the study settings.
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尼日利亚东北部2型糖尿病患者心血管危险因素及处方模式
心血管疾病是糖尿病患者发病和死亡的主要原因。本研究对2017年6月至2018年5月期间在尼日利亚东北部两家转诊医院就诊的成年(>18岁)2型糖尿病患者的病例文件夹进行了为期12个月的回顾性横断面审计。检索患者的社会人口学特征、心血管危险因素、用药史和临床特征等资料。数据以比例和百分比的形式以表格和饼状图的形式呈现。分析使用社会科学统计软件包(SPSS) 21.0版完成。在807个病例文件夹中,64.5%为女性患者,大多数(61.3%)年龄在50岁以下,90.2%为已婚。超过50%的人受过中学/小学教育,大多数(57.9%)是非技术工人。约三分之一(34.6%)从事中度至定期体育活动。高血压患病率为84.8%,血脂异常患病率为5.1%,肥胖患病率为47.1%。超过四分之三(87%)的患者服用多种口服降糖药,其中二甲双胍是处方最多的药物(93.8%)。降压药处方率最高的是赖诺普利(57.9%),低剂量乙酰水杨酸、降脂药和普瑞巴林的处方率分别为50.9%、6.5%和2.7%。高血压是研究人群中最普遍的心血管危险因素,其次是超重/肥胖。二甲双胍和赖诺普利的处方率是值得赞扬的,但在研究环境中需要增加他汀类药物和普瑞巴林的使用。
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