Organochlorine pesticide residues in human milk samples from women living in Northwest and Northeast Mississippi, 1973-75.

Pesticides monitoring journal Pub Date : 1979-09-01
R W Barnett, A J D'Ercole, J D Cain, R D Arthur
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Abstract

Organochlorine pesticide analyses were performed on human milk samples obtained from 34 women living in the Mississippi Delta, a high pesticide usage area, and from six women living in Starkville, Mississippi, a low pesticide usage area. Nine women collected samples before and after their babies had nursed so that fat levels and sigma DDT levels could be compared on whole milk and milk fat bases. sigma DDT values were independent of collection time if calculated on a milk fat basis, but not if calculated on a whole milk basis. Thus, the most consistent indicator of DDT residues were values calculated on a milk fat basis. Residue levels for p,p'-DDE, p,p'-DDT, and sigma DDT were significantly different (P less than 0.01) in samples from the two areas. Residues of o,p'-DDT, beta-BHC, and oxychlordane in milk samples from women living in the high pesticide usage area also were significantly different (P less than 0.05). A mean value of 19.17 ppm sigma DDT, found in the milk fat of samples from the high pesticide usage area, is the highest ever reported. Samples from the low pesticide usage area contained a mean level of 2.36 ppm sigma DDT.

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1973- 1975年密西西比州西北部和东北部妇女母乳中有机氯农药残留的研究。
研究人员对34名生活在密西西比三角洲的妇女和6名生活在密西西比州斯塔克维尔的妇女的母乳样本进行了有机氯农药分析,这是一个农药使用量高的地区,而密西西比州斯塔克维尔是一个农药使用量低的地区。九名妇女在婴儿喂养前后收集了样本,以便比较全脂牛奶和乳脂基础上的脂肪水平和sigma DDT水平。如果以乳脂为基础计算,sigma DDT值与收集时间无关,但如果以全脂牛奶为基础计算,则无关。因此,最一致的滴滴涕残留指标是以乳脂为基础计算的值。p、p′-DDE、p、p′-DDT和sigma DDT的残留水平在两个地区的样品中存在显著差异(p < 0.01)。农药高使用率地区妇女乳样中o、p’-滴滴涕、-六六六、氧氯丹残留量差异也有统计学意义(p < 0.05)。在高农药使用地区的乳脂样本中发现的滴滴涕均值为19.17 ppm西格玛,是有史以来最高的。来自低农药使用地区的样本中DDT的平均水平为2.36 ppm sigma。
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