Hipótesis neuroinvasiva en un caso de delirium atípico en paciente con neumonía por COVID-19

Q4 Medicine Psiquiatria Biologica Pub Date : 2021-01-01 DOI:10.1016/j.psiq.2020.10.001
Ana Izquierdo Zarazaga, Eduardo Delgado Parada, Maite Santamaría Núñez, Alberto López Cruz, María Pardo Corral, Álvaro Ximénez-Carrillo Rico
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引用次数: 1

Abstract

Objective

Delirium is the most frequent neuropsychiatric complication in patients with a severe condition caused by COVID-19. We present an atypical case from a clinical and phenomenological point of view, and we reflect on the involved etiological mechanisms.

Clinical case

55-year-old male, active physician, first admitted into the conventional hospitalization unit and is clinically stable after being admitted into the Intensive Care Unit for pneumonia caused by severe COVID-19. He presents an atypical delirium with very significant memory and language disorders, which are measured psychometrically, while maintaining a good attention and alertness level. The rest of the complementary tests carried out are normal or not very conclusive.

Results

The evolution during his admission is good and the recovery complete after one month of being discharged from the hospital.

Conclusions

The atypical presentation and clinical evolution of this framework of delirium allow us to raise the question of the direct neuroinvasive role of COVID-19 in this case.

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目的谵妄是COVID-19重症患者最常见的神经精神并发症。我们从临床和现象学的角度提出一个非典型病例,并对涉及的病因机制进行了反思。临床病例男,55岁,在职医师,首次入住常规住院单元,因新型冠状病毒感染症(COVID-19)重症肺炎入住重症监护室后临床稳定。他表现出一种非典型谵妄伴有非常严重的记忆和语言障碍,这是心理测量学测量的,同时保持着良好的注意力和警觉性水平。其余的补充检查都是正常的,或者不是很确定。结果住院期间病情发展良好,出院1个月后恢复完全。结论该谵妄框架的非典型表现和临床演变使我们提出了COVID-19在该病例中的直接神经侵袭作用的问题。
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来源期刊
Psiquiatria Biologica
Psiquiatria Biologica Medicine-Psychiatry and Mental Health
CiteScore
0.40
自引率
0.00%
发文量
13
期刊介绍: Es la Publicación Oficial de la Sociedad Española de Psiquiatría Biológica. Los recientes avances en el conocimiento de la bioquímica y de la fisiología cerebrales y el progreso en general en el campo de las neurociencias han abierto el camino al desarrollo de la psiquiatría biológica, fundada sobre bases anatomofisiológicas, más sólidas y científicas que la psiquiatría tradicional.
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