Thyroid cancer in Sardinian pediatric patients: report of 63 cases and a review of the literature

M. Lai, A. Satta, G. Pinna, L.M. Altana, G. Senes, P. Coni, G. Faa
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Abstract

Thyroid cancer is considered uncommon in pediatrics, yet it is the most common endocrine malignancy among them. The aim of this study was to analyze pediatric thyroid carcinomas diagnosed in Sardinian children and adolescents in order to find a possible association with autoimmune diseases. We studied 63 consecutive 10-20-years-old patients who underwent surgery for thyroid cancer between January 2001 and April 2020 in our hospital. No evidence of risk factors including external radiation was found. All cases were follicular-derived neoplasms: 45 PTCs (72%), 9 FTCs (14%), 2 well differentiated carcinomas not otherwise specified (3%), 2 poorly differentiated carcinomas (3%), 5 cases of encapsulated PTC-FV were re-diagnosed as NIFTP
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撒丁岛儿童甲状腺癌:63例报告及文献回顾
甲状腺癌在儿科中并不常见,但却是最常见的内分泌恶性肿瘤。本研究的目的是分析撒丁岛儿童和青少年诊断的儿童甲状腺癌,以发现其与自身免疫性疾病的可能关联。我们研究了2001年1月至2020年4月在我院连续接受甲状腺癌手术的63例10-20岁患者。没有发现包括外部辐射在内的危险因素的证据。所有病例均为滤泡源性肿瘤:45例ptc(72%), 9例ftc(14%), 2例未明确的高分化癌(3%),2例低分化癌(3%),5例包膜PTC-FV重新诊断为NIFTP
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