Effect of a long term oral administration of a hypercholesterolic diet on rat liver substructures.

C Pignatti, E F Levi, M Cocchi
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Abstract

The effects of high cholesterol diets on ultrastructure morphologic alterations of rat liver have been investigated. It has been verified that these diets induce the biochemical and morphological damage, as well as death in a shorter time than alipidic or sole saturated lipid diets. Moreover it has been established that the anatomic irreversible damage appears at the last stage, just before death.

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长期口服高胆固醇饮食对大鼠肝脏亚结构的影响。
本文研究了高胆固醇饮食对大鼠肝脏超微结构形态学改变的影响。研究证实,与脂类或单一饱和脂类饲料相比,这些饲料可在更短的时间内引起生物化学和形态损伤以及死亡。此外,已经确定,解剖上的不可逆损伤出现在死亡前的最后阶段。
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