Diurnal variation in uterine estrogen receptors in immature female rats--inhibition by arginine vasotocin.

M K Vaughan, J Buchanan, D E Blask, R J Reiter, P J Sheridan
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引用次数: 8

Abstract

A diurnal variation in uterine estrogen receptors from immature female rats was observed with the peak occurring during the mid-light phase (noon) of the cycle. Although no dose response was noted, all concentrations of arginine vasotocin ranging from 5 x 10(-7) to 5 x 10(-9) significantly inhibited binding of 3H-estradiol to estrogen receptors in the cytosol fraction of uteri obtained from immature female rats either during the light or dark phase of the photoperiod.

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未成熟雌性大鼠子宫雌激素受体的日变化——精氨酸缩宫素的抑制作用。
未成熟雌性大鼠子宫雌激素受体呈昼夜变化,高峰出现在月经周期的中光期(中午)。尽管没有发现剂量反应,但在光周期的亮期或暗期,从5 × 10(-7)到5 × 10(-9)范围内的所有精氨酸缩宫素浓度都能显著抑制未成熟雌性大鼠子宫细胞质部分中3h -雌二醇与雌激素受体的结合。
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