Genetic variation in testicular LH receptors in the mouse.

A Amador, A Bartke, W Beamer
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引用次数: 5

Abstract

The concentration of testicular hCG (LH) binding sites was measured in five mutants with defective endocrine and/or reproductive functions, in a hypoandrogenic inbred strain and in six normal strains. A decrease in hCG binding was found in dw/dw mice, and an increase in Tfm/y and C57Bl10/J mice. Analysis of the results indicates the existence of a genetic factor(s) involved in the regulation of hCG (LH) binding.

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小鼠睾丸LH受体的遗传变异。
测定了5个内分泌和/或生殖功能有缺陷的突变体、1个低雄激素自交系和6个正常菌株的睾丸hCG (LH)结合位点的浓度。dw/dw小鼠hCG结合降低,Tfm/y和C57Bl10/J升高。分析结果表明,存在一种遗传因素参与调节hCG (LH)结合。
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