Antitumor Plants. V. Constituents of Cinchona pubescens.

Lloydia Pub Date : 1978-09-01
R F Raffauf, P W Le Quesne, P C Ghosh
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Abstract

The stem bark and stem wood of Cinchona pubescens were found to owe their weak cytotoxic activity to the presence of quinovic acid. This acid and its 3-rhamnoside were isolated and characterized through several derivatives, all of which were assayed for their cytotoxicity.

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抗肿瘤植物。五。金鸡纳短毛的成分。
研究发现,金鸡纳茎皮和茎材的细胞毒活性较弱是由于奎诺维奇酸的存在。对该酸及其3-鼠李糖苷进行了分离和鉴定,并对其进行了细胞毒性测定。
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Plants used against cancer. A survey. Inhibition of reverse transcriptase activity by benzophenanthridine alkaloids. (+)Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica. Proceedings of the 19th Annual Meeting of the American Society of Pharmacognosy held with the Phytochemical Society of North America, August 14-17, 1978, Oklahoma State University, Stillwater, Oklahoma. Plant antitumor agents. XVI. 6alpha-Senecioyloxy-chaparrinone, a new antileukemic quassinoid from Simaba multiflora.
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