{"title":"Duodenal motility after cholecystokinin injection or satiety","authors":"J.A. Deutsch, T.R. Thiel, L.H. Greenberg","doi":"10.1016/S0091-6773(79)90262-1","DOIUrl":null,"url":null,"abstract":"<div><p>Rats were implanted with a photocell on one side of the duodenum and a light emitting diode on the other. This permitted recordings of upper duodenal activity in the freely moving animal. Such recordings were made when rats were injected with the terminal octapeptide of cholecystokinin or saline as they fed to satiety. While cholecystokinin reduced intake by over 50%, the amplitude of duodenal activity after cholecystokinin injection was grossly attenuated as compared with activity after normal satiation. Food intake reduction after cholecystokinin injection may therefore be due to this abnormality rather than normal satiety.</p></div>","PeriodicalId":75577,"journal":{"name":"Behavioral biology","volume":"24 3","pages":"Pages 393-399"},"PeriodicalIF":0.0000,"publicationDate":"1978-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0091-6773(79)90262-1","citationCount":"26","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavioral biology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0091677379902621","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 26
Abstract
Rats were implanted with a photocell on one side of the duodenum and a light emitting diode on the other. This permitted recordings of upper duodenal activity in the freely moving animal. Such recordings were made when rats were injected with the terminal octapeptide of cholecystokinin or saline as they fed to satiety. While cholecystokinin reduced intake by over 50%, the amplitude of duodenal activity after cholecystokinin injection was grossly attenuated as compared with activity after normal satiation. Food intake reduction after cholecystokinin injection may therefore be due to this abnormality rather than normal satiety.
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