{"title":"Saline intake in hamsters","authors":"Roderick Wong, Wayne Jones","doi":"10.1016/S0091-6773(78)90823-4","DOIUrl":null,"url":null,"abstract":"<div><p>Experiment 1 assessed the preference-aversion function of hamsters for water and 0.08, 0.15, 0.35, and 0.71 <em>M</em> NaCl solutions in the two-bottle test. Unlike rats, the hamsters did not show a strong preference for isotonic (0.15 <em>M</em>) saline, nor did they exhibit any preference for the other solutions. Experiment 2 examined the effects of hydrochlorothiazide on the hamsters' intake of 0.71 M NaCl solution. The results indicated that this diuretic agent did not cause the hamsters to increase their saline intake relative to the baseline level. Experiment 3 also indicated that a high (5 mg) dose of desoxycorticosterone acetate failed to produce sodium appetite in the hamsters. These results contrast with those found with rats.</p></div>","PeriodicalId":75577,"journal":{"name":"Behavioral biology","volume":"24 4","pages":"Pages 474-480"},"PeriodicalIF":0.0000,"publicationDate":"1978-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0091-6773(78)90823-4","citationCount":"10","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavioral biology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0091677378908234","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 10
Abstract
Experiment 1 assessed the preference-aversion function of hamsters for water and 0.08, 0.15, 0.35, and 0.71 M NaCl solutions in the two-bottle test. Unlike rats, the hamsters did not show a strong preference for isotonic (0.15 M) saline, nor did they exhibit any preference for the other solutions. Experiment 2 examined the effects of hydrochlorothiazide on the hamsters' intake of 0.71 M NaCl solution. The results indicated that this diuretic agent did not cause the hamsters to increase their saline intake relative to the baseline level. Experiment 3 also indicated that a high (5 mg) dose of desoxycorticosterone acetate failed to produce sodium appetite in the hamsters. These results contrast with those found with rats.
实验1评估了两瓶试验中仓鼠对水和0.08、0.15、0.35、0.71 M NaCl溶液的偏好厌恶功能。与大鼠不同，仓鼠对等渗(0.15 M)盐水没有表现出强烈的偏好，对其他溶液也没有表现出任何偏好。实验2考察氢氯噻嗪对仓鼠0.71 M NaCl溶液摄取量的影响。结果表明，这种利尿剂并没有使仓鼠的生理盐水摄入量相对于基线水平增加。实验3还表明，高剂量(5毫克)的醋酸去氧皮质酮不能使仓鼠对钠产生食欲。这些结果与在老鼠身上发现的结果相反。
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