[Tumor immunology (author's transl)].

Pathologia et microbiologia Pub Date : 1975-01-01
S Barandun, A Morell
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Abstract

Prerequisites for immunobiological interactions between host and tumor are the existence of tumor-specific surface antigens on cancer cells on the one hand, and the ability of the host to recognize and to adequately respond to these signals on the other. It seems that in certain selected animal models these conditions are matched. The relations of the spontaneously arising human tumors to these prerequisites, however, are still largely obscure. It is known that immunological measures can both accelerate or inhibit tumor growth. Thus, immunoprophylaxis and immunotherapy in man is still premature and too risky.

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[肿瘤免疫学(作者译)]。
宿主与肿瘤发生免疫生物学相互作用的先决条件一方面是癌细胞表面存在肿瘤特异性抗原,另一方面是宿主对这些信号的识别和充分反应能力。在某些选定的动物模型中,这些条件似乎是匹配的。然而,自发产生的人类肿瘤与这些先决条件的关系在很大程度上仍然是模糊的。众所周知,免疫措施可以加速或抑制肿瘤的生长。因此,免疫预防和免疫治疗在男性仍然是不成熟的和太危险。
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