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Pathologia et microbiologia最新文献

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Endarteritis obliterans or arteriosclerosis obliterans.
Pathologia et microbiologia
Pub Date : 1975-07-01 DOI: 10.1159/000162815
A. Kádár, H. Jellinek, Z. Béres
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引用次数: 2
Marfan's disease. 马方氏病。
Pathologia et microbiologia
Pub Date : 1975-07-01 DOI: 10.1159/000162805
E. Olsen
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引用次数: 2
Proceedings: The epidemic of primary pulmonary hypertension in Europe. 欧洲原发性肺动脉高压的流行
Pathologia et microbiologia
Pub Date : 1975-07-01 DOI: 10.1159/000162831
E. Lüthy
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引用次数: 8
Extracranial giant cell arteritis. 颅外巨细胞动脉炎。
Pathologia et microbiologia
Pub Date : 1975-01-01 DOI: 10.1159/000162818
H J Leu, G Garzoli
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引用次数: 12
F antigen. III. Immunological and biological properties. F抗原。3免疫学和生物学特性。
Pathologia et microbiologia
Pub Date : 1975-01-01
R Utzinger

Relationship of the isoforms of F antigens from A2G and CBA inbred mouse strains have been worked out in detail in respect to their immunogenicity. Mice from several inbred strains have been shown to possess the ability of forming anti-F upon stimulation with xenogeneic F antigens from certain species. An immunoelectrophoretic method for sensitive quantitation of the antigen is described. During human ontogenesis the antigen appears very early. It could never be detected in serum except in cases of acute liver disease. A small fragment set free under denaturing conditions showed the ability of inhibiting precipitation of the complete antigen by antibody. The F protein seems to be a vehicle for this small fragment possessing haptenic properties and probably being responsible for the universal cross-reactivity.

详细分析了A2G和CBA近交系小鼠F抗原同工型在免疫原性方面的关系。来自几个近交系的小鼠已被证明在受到来自某些物种的异种F抗原刺激时具有形成抗F的能力。描述了一种抗原敏感定量的免疫电泳方法。在人类个体发育过程中，抗原很早就出现了。除非在急性肝病的情况下，它永远不能在血清中检测到。在变性条件下释放的小片段显示出抑制抗体沉淀完整抗原的能力。F蛋白似乎是这个具有半抗原特性的小片段的载体，可能是造成普遍交叉反应的原因。
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引用次数: 0
Proceedings: Synergism between 5-fluorocytosine and polyene antibiotics. 进展:5-氟胞嘧啶与多烯抗生素的协同作用。
Pathologia et microbiologia
Pub Date : 1975-01-01 DOI: 10.1159/000162761
A Polak
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引用次数: 3
Fine structural changes in embryonic chick heart ventricle induced by lead poisoning. 铅中毒致胚胎鸡心脏心室微细结构改变。
Pathologia et microbiologia
Pub Date : 1975-01-01 DOI: 10.1159/000162738
S H Gilani

The embryonic chick heart ventricle of day 11 was studied electron microscopically to learn the structural changes that develop in lead poisoning. The chick embryos were administered with 0.015 mg/egg of lead acetate at day 2. The most pronounced changes observed in the ventricle were: malformed mitochondria, disorganized, short and scanty myofibrils and abundance of swollen vacuoles. The ultrastructure of the ventricle from the control chick embryos was normal. The most frequent change noted in the ventricular tissue was an alteration in the myofibrils. This study indicates that electron microscopic changes can be induced in the embryonic chick heart ventricle by lead poisoning.

采用电子显微镜观察了铅中毒后第11天胚鸡心脏心室的结构变化。第2天，鸡胚中添加0.015 mg/蛋的醋酸铅。心室最明显的变化是:线粒体畸形，组织紊乱，肌原纤维短而少，空泡肿胀。对照鸡胚心室超微结构正常。心室组织中最常见的改变是肌原纤维的改变。本研究表明，铅中毒可引起胚胎鸡心脏心室的电镜变化。
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引用次数: 1
[Morphology of myometrial and decidual arteries in normal pregnancy, in toxemia of pregnancy, and in maternal diabetes (author's transl)]. [正常妊娠、妊娠毒血症和孕妇糖尿病的子宫肌层和蜕膜动脉形态(作者译)]。
Pathologia et microbiologia
Pub Date : 1975-01-01
P Emmrich, R Birke, E Gödel

127 specimens, obtained by different methods from the myometrium and the placental bed after parturition, are investigated histologically. This material includes normal pregnancies as well as cases of maternal diabetes with and without hypertension and cases of hypertension in EPH-gestosis. The different parts of the arterial system (spiral arteries, basal arteries, radial arteries) are separately investigated. Physiologically, the pregnancy induces changes in the wall of the decidual arteries and possibly in the distal part of the radial arteries. The fibromuscular layer including the elastic fibers were destructed and replaced by fibrin and connective tissue. For this reason, in these parts of arteries it is very difficult to separate pathological from physiological changes.

本文采用不同方法对分娩后子宫肌层和胎盘床的127个标本进行组织学研究。这些资料包括正常妊娠，以及伴有和不伴有高血压的产妇糖尿病病例，以及妊高征妊娠期高血压病例。动脉系统的不同部分(螺旋动脉、基底动脉、桡动脉)分别进行研究。生理上，妊娠引起蜕膜动脉壁的改变，也可能是桡动脉远端部分的改变。纤维肌层包括弹性纤维被破坏，取而代之的是纤维蛋白和结缔组织。因此，在动脉的这些部位很难将病理性变化与生理性变化区分开来。
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引用次数: 0
Unexplained pulmonary hypertension. 原因不明的肺动脉高压。
Pathologia et microbiologia
Pub Date : 1975-01-01
C A Wagenvoort
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引用次数: 0
[Pathophysiological implications of antigen-antibody complexes (author's transl)]. [抗原抗体复合物的病理生理意义(作者译)]。
Pathologia et microbiologia
Pub Date : 1975-01-01
R Zubler, U E Nydegger, S Izui, P H Lambert, P A Miescher

Seventy years after the description of the Arthus phenomenon, the concept of immune complex mediated pathology is widely recognized in clinical pathophysiology. The availability of methods for the detection of soluble immune complexes opens new paths for clinical investigation in this field. This is demonstrated for systemic lupus erythematosus, viral hepatitis B and herpes zoster disease. New experimental approaches deal with the question of tissue localization of immune complex mediated diseases, e.g. through affinity of antigens for certain tissue structures.

在Arthus现象被描述70年后，免疫复合物介导的病理概念在临床病理生理学中得到广泛认可。可溶性免疫复合物检测方法的可用性为该领域的临床研究开辟了新的途径。这在系统性红斑狼疮、病毒性乙型肝炎和带状疱疹疾病中得到证实。新的实验方法处理免疫复合物介导的疾病的组织定位问题，例如通过抗原对某些组织结构的亲和力。
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引用次数: 0
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