EFFECTIVENESS OF 5% GUAVA LEAF (Psidium guajava Linn) EXTRACT OF WHITE FRUIT VARIANT TO DECREASE LEVELS OF Volatile Sulfur Compounds (VSCs) IN HALITOSIS SUFFERERS

Melina Vania Elian, Nuzulia Irawati, S. Nelis
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Abstract

Halitosis is a general term used to describe the bad breath coming out of the oral cavity. Volatile Sulfur Compounds (VSCs) are a major component causes of halitosis, formed from the break down of protein substrate by gram-negative anaerobes such as Porphyromonas gingivalis, Tanerella forsythia, Fusobacterium nucleatum, Prevotella intermedia and Treponema denticola. Guava leaf (Psidium guajava Linn) contain high levels of quercetin compounds that can inhibit the growth of Porphyromonas gingivalis and Prevotella intermedia. This study aims to determine the effectiveness of 5% guava leaf (Psidium guajava linn) extract of white fruit variant to decrease levels of Volatile Sulfur Compounds (VSCs) in halitosis sufferers. This research method was pre-experimental which consists of 19 subjects. The guava leaf (Psidium guajava Linn) extract was made by maceration method and diluted with distiled water at 5% concentration. The levels of Volatile Sulfur Compounds (VSCs) were measured by breath checker before (pre test) and after (post test) treatment. Wilcoxon test showed that there was a significant difference between the levels of Volatile Sulfur Compounds (VSCs) before and after gargling with 5% guava leaf (Psidium guajava Linn) extract of white fruit variant (p<0,05). The conclusion of this research was 5% guava leaf (Psidium guajava Linn) extract of white fruit variant effectively decreases levels of Volatile Sulfur Compounds (VSCs) in halitosis sufferers.
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5%番石榴叶提取物对降低口臭患者挥发性硫化合物(VSCs)水平的有效性
口臭是一个通用术语,用来描述口腔中出现的口臭。挥发性硫化合物(VSCs)是口臭的主要原因,由革兰氏阴性厌氧菌如牙龈卟啉单胞菌、连翘Tanerella、核梭杆菌、中普雷沃氏菌和齿状螺旋体分解蛋白质底物形成。番石榴叶(Psidium guajava Linn)含有高水平的槲皮素化合物,可以抑制牙龈卟啉单胞菌和中间普氏菌的生长。本研究旨在确定5%番石榴叶(Psidium guajava linn)提取物对降低口臭患者挥发性硫化合物(VSCs)水平的有效性。本研究方法为预实验,共19名受试者。采用浸渍法制备番石榴叶提取物,用5%浓度的蒸馏水稀释。在治疗前(测试前)和治疗后(测试后)通过呼吸检测器测量挥发性硫化合物(VSCs)的水平。Wilcoxon检验显示,5%番石榴叶(Psidium guajava Linn)白果变体提取物漱口前后挥发性硫化合物(VSCs)含量差异有统计学意义(p< 0.05)。本研究的结论是,5%番石榴叶(Psidium guajava Linn)白果变体提取物可有效降低口臭患者的挥发性硫化合物(VSCs)水平。
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