Development of microfluidic chips based on magnetic nano-materials in biomedical applications

W. L, Chun-mei Mao, Jin-hui Yu, Zuo-jun Sun
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Abstract

Microfluidic devices appear to offer important opportunities for modern research, especially for the clinical diagnosis, drug delivery and biomedicine research due to their numerous advantages, such as very low reagent consumption and waste generation, fast reaction time, high reaction efficiency and a large surface to volume ratio. Therefore, microfluidic have been paid much more attention by the researchers in recent years. Functionalized magnetic nano-particles can be used for a large number of microfluidic applications and have attracted a great attention during the last few years because of their unique properties of tunable anisotropic interaction. This paper reviews the development of microfluidic chips based on magnetic nano-materials in biomedical applications. The future research directions of microfluidic as well as their applications were also discussed.
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基于磁性纳米材料的生物医学微流控芯片的研制
微流控装置由于其试剂消耗和废物产生极低、反应时间快、反应效率高、表面体积比大等诸多优点,为现代研究,特别是临床诊断、药物输送和生物医学研究提供了重要的机会。因此,近年来微流控技术越来越受到研究人员的关注。功能化磁性纳米粒子具有可调各向异性相互作用的特性,近年来在微流控领域得到了广泛的应用。本文综述了基于磁性纳米材料的微流控芯片在生物医学领域的应用进展。最后对微流体的研究方向及其应用进行了展望。
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