Accidental Trihexyphenidyl Intoxication in a Seven-Year-Old Child: A Case Report from Senegal

D. I, P. V., Boiro D
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Abstract

Trihexyphenidyl or Artane® /Parkinane® is an anti-cholinergic drug belonging to the antimuscarinic class. It is used in the treatment of Parkinson’s disease and widely in psychiatry for the management of extrapyramidal side effects of neuroleptics. Its overdose leads to a central and peripheral anticholinergic syndrome. We report here the case of a seven-year-old Senegalese boy who developed signs of intoxication due to accidental ingestion of a high dose of trihexyphenidyl and recovered completely after administration of parenteral antipyretic, gastric lavage and supportive care in a paediatric setting.
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塞内加尔7岁儿童意外中毒1例
Trihexyphenidyl或Artane®/Parkinane®是一种抗胆碱能药物,属于抗uscarinic类。它被广泛用于治疗帕金森氏症,并在精神病学中广泛用于治疗抗精神病药的锥体外系副作用。过量服用可导致中枢和外周抗胆碱能综合征。我们在此报告一个7岁的塞内加尔男孩,由于意外摄入高剂量的三己苯基而出现中毒症状,并在儿科接受肠外解热药、洗胃和支持治疗后完全恢复。
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