1704 Identifying clusters of longitudinal autoantibody profiles associated with systemic lupus erythematosus disease outcomes

M. Choi, Irene K. Chen, A. Clarke, M. Fritzler, K. Buhler, M. Urowitz, J. Hanly, C. Gordon, Y. Pierre, S. Bae, J. Diaz, J. Sánchez-Guerrero, S. Bernatsky, D. Wallace, D. Isenberg, Anisur Rahman, J. Merrill, P. Fortin, D. Gladman, I. Bruce, M. Petri, E. Ginzler, M. Dooley, R. Ramsey‐Goldman, S. Manzi, A. Jonsen, G. Alarcón, R. Vollenhoven, C. Aranow, M. Mackay, G. Ruiz‐Irastorza, Sam Lim, M. Inanç, K. Kalunian, S. Jacobsen, C. Peschken, D. Kamen, A. Askanase, D. Sontag, J. Buyon, K. Costenbader
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1704确定与系统性红斑狼疮疾病结局相关的纵向自身抗体谱簇
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1706 A model of lupus pathogenesis: anti-EBNA1 heteroantibodies initiate lupus by cross reacting with lupus autoantigens, resulting in lupus autoantibodies and clinical disease 1704 Identifying clusters of longitudinal autoantibody profiles associated with systemic lupus erythematosus disease outcomes 1703 Activated PI3Kδ signals compromise plasma cell survival via limiting autophagy and increasing endoplasmic reticulum stress 1701 Curli amyloid/DNA complexes from bacterial biofilms break tolerance in murine lupus using T cell-independent and T cell-dependent modalities 1705 Protein assemblages are newly described intracellular structures that may play a role in shaping the lupus autoantibody repertoire
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