MSRCN: Multi-task Learning Network for Cell Segmentation and Regression Counting

Lihua Huang, Liqin Huang, Mingjing Yang
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Abstract

Accurate cell segmentation and counting play an important role in medical diagnosis. However, the size and shape of cells are varied largely, and the presence of overlapping cells complicates cell counting. Recent studies have shown that multi-task learning methods perform well in deep learning. In specific, we design Multi-task Segmentation Regression Counting Network (MSRCN). For cell segmentation, a multi-scale attention mechanism module is designed to suppress irrelevant regions and learns salient features for a specific task. For cell counting, a regression model is utilized to learn a mapping from cell feature information to target counts. The proposed MSRCN model is analyzed and compared with other states of the art cell segmentation methods and cell counting methods. MSRCN outperforms these methods in all evaluation metrics. The Dice similarity coefficient, root mean square error, and mean absolute error of the proposed method is 0.9316, 2.1215, and 1.5927, respectively. The experiments results show that the proposed method not only improves the functioning of cell segmentation, but also outperforms direct regression counting methods in terms of cell counting.
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用于细胞分割和回归计数的多任务学习网络
准确的细胞分割和计数在医学诊断中起着重要的作用。然而,细胞的大小和形状变化很大,细胞重叠的存在使细胞计数复杂化。最近的研究表明,多任务学习方法在深度学习中表现良好。具体而言,我们设计了多任务分割回归计数网络(MSRCN)。对于细胞分割,设计了一个多尺度注意机制模块来抑制不相关区域并学习特定任务的显著特征。对于细胞计数,使用回归模型学习从细胞特征信息到目标计数的映射。对所提出的MSRCN模型进行了分析,并与其他先进的细胞分割方法和细胞计数方法进行了比较。MSRCN在所有评估指标上都优于这些方法。该方法的Dice相似系数为0.9316,均方根误差为2.1215,平均绝对误差为1.5927。实验结果表明,该方法不仅提高了细胞分割的功能,而且在细胞计数方面优于直接回归计数方法。
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