[Indication for splenectomy and exploration of the abdomen in Hodgkin's disease (author's transl)].

R Revol, C Alexandre, J J Viala, J Favre-Gilly
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Abstract

Splenectomies were performed on 142 patients (86 men and 56 women). The majority of them (117) were stages III or IV. The purpose of the laparotomy was therapeutic and not exploratory. Surgery was indicated, either due to evolution of the disease suggesting splenic involvement or to symptoms of hypersplenism. Splenic involvement was confirmed in 71% and hepatic involvement in 40%. Despite the risk of mortality during the first month after surgery, proportional to the extent of the disease, the overall results are encouraging provided that surgical intervention is followed by aggressive polychemotherapy. Serious infections were observed, however, in 9 patients; they did not occur for several months or even several years after splenectomy.

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[何杰金氏病脾切除及腹部探查的指征[作者简介]。
142例患者行脾切除术(男86例,女56例)。其中大多数(117)为III期或IV期。开腹手术的目的是治疗性的,而不是探索性的。由于疾病的发展表明脾脏受累或脾功能亢进的症状,需要手术治疗。脾受累71%,肝受累40%。尽管手术后第一个月的死亡风险与疾病的程度成正比,但如果手术干预后进行积极的多化疗,总体结果是令人鼓舞的。严重感染9例;脾切除术后几个月甚至几年都没有发生。
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