Application of polar stationary phases OV-225 and OV-275 in the detection of drugs in urine samples

G.L. Dadisch, W. Vycudilik, G. Machata
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引用次数: 10

Abstract

A procedure for fast screening of urine samples is described. TLC and GC equipped with NPD enable detection of therapeutic doses of drugs to be made in a short time. Tables of retention values for TLC and GC are also presented. TLC detects drugs with a sequence of three reagents. GC screening is carried out with a temperature programmed run of 30 °C/min up to 290 °C. For the determination of retention indices new polar phases with suitable thermal stabilities such as OV-225 and OV-275 are used.

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极性固定相OV-225和OV-275在尿液中药物检测中的应用
本文描述了一种快速筛选尿样的方法。配备NPD的薄层色谱和气相色谱可以在短时间内检测出所需药物的治疗剂量。并给出了薄层色谱和气相色谱的保留值表。TLC用三种试剂的序列来检测药物。GC筛选在30°C/min至290°C的温度程序运行下进行。保留指数的测定采用了热稳定性较好的极性相OV-225和OV-275。
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