Pub Date : 1978-05-01DOI: 10.1016/S0379-0738(78)80052-8
Elisabeth Trube-Becker
At post mortems performed in cases of cot death, the cause of death has been established as due to a variety of pathological changes. In connection with the anamnesis data, inflammation in the region of the respiratory system, especially of the lungs, infections of the gastrointestinal tract, otitis media and electrolyte shifts can in many cases be traced back to a common origin, if we assume a bacterioenterotoxin poisoning (which takes a different course in infants than in older children or adults).
Extensive inquiries prior to the post mortem, autopsies performed always by the same method, as well as all the ensuing examinations, are indispensable in order to explain the cause of the sudden death and to make sure that the results of the post mortem are not influenced by the importance the pathologist attributes to a certain method of examination.
Bei der Obduktion plötzlich verstorbener Säuglinge wird eine Vielfalt krankhafter Veränderungen als Ursache des Todes festgestellt. Entzündungen im Bereich der Atemwege, insbesondere der Lungen, Infekte des Magen-Darmtraktes, Otitis media, Elektrolytverschiebungen, in letzter Zeit auch sogenanntes gelbes Fett u.a. können in Zusammenwirken mit den Angaben zur Vorgeschichte in vielen Fällen durch die Annahme einer Bakterien-Enterotoxinvergiftung, die im Säuglingsalter anders verläuft als beim grösseren Kind oder Erwachsenen, auf einen gemeinsamen Ursprung zurückgeführt werden.
Ausführliche Ermittlungen vor der Obduktion, die in gleicher Art und Weise durchgeführte Leichenöffnung sowie der sich daran anschliessender Untersuchungen sind für die Klärung der Ursache des plötzlichen Todes unabdingbare Voraussetzunge, schon damit die Ergebnisse nicht der Bedeutung, die der Obduzent einer bestimmten Untersuchungsmethode beimisst, entsprechen.
在对婴儿猝死病例进行尸检时,已确定死因是由于各种病理变化。与记忆数据相关的是,如果我们假设是细菌肠毒素中毒(婴儿与年龄较大的儿童或成人的病程不同),那么在许多情况下,呼吸系统区域的炎症,特别是肺部的炎症、胃肠道感染、中耳炎和电解质变化可以追溯到一个共同的起源。为了解释突然死亡的原因和确保尸检结果不受病理学家认为某种检验方法的重要性的影响,在验尸前进行广泛的询问、总是用同一种方法进行的尸检以及随后进行的所有检查都是必不可少的。beder Obduktion plötzlich verstorbener Säuglinge wind eine vilelfalt krankhafter Veränderungen als Ursache des Todes festgestellt。entz ndungen im Bereich der Atemwege, insbesonere der Lungen, Infekte des Magen-Darmtraktes, Otitis media, Elektrolytverschiebungen, in letzter Zeit auth sogenannes gelbes Fett u.a. können in Zusammenwirken mit den Angaben zur Vorgeschichte in vielen Fällen durch die Annahme einer Bakterien-Enterotoxinvergiftung, die in Säuglingsalter anders verläuft als beim grösseren Kind oder Erwachsenen, auf einen gemeinsamen Ursprung zurckgef hrt werden。ausf hrliche Ermittlungen vor der beimisist, entprerechen, die in gleicher Art und Weise durchgegef, die in gleicher Art und Weise durchgef, die in gleicher Art und Weise durchgef, die in gleicher Art und Weise durchgef, die in gleicher Art and Weise durchgegehessender untersususetzunge, die der Ursache des plötzlichen, die der Obduzent beimisist, entprerechen。
{"title":"Enteral bacterial infection as a possible cause of cot death","authors":"Elisabeth Trube-Becker","doi":"10.1016/S0379-0738(78)80052-8","DOIUrl":"10.1016/S0379-0738(78)80052-8","url":null,"abstract":"<div><p>At post mortems performed in cases of cot death, the cause of death has been established as due to a variety of pathological changes. In connection with the anamnesis data, inflammation in the region of the respiratory system, especially of the lungs, infections of the gastrointestinal tract, otitis media and electrolyte shifts can in many cases be traced back to a common origin, if we assume a bacterioenterotoxin poisoning (which takes a different course in infants than in older children or adults).</p><p>Extensive inquiries prior to the post mortem, autopsies performed always by the same method, as well as all the ensuing examinations, are indispensable in order to explain the cause of the sudden death and to make sure that the results of the post mortem are not influenced by the importance the pathologist attributes to a certain method of examination.</p></div><div><p>Bei der Obduktion plötzlich verstorbener Säuglinge wird eine Vielfalt krankhafter Veränderungen als Ursache des Todes festgestellt. Entzündungen im Bereich der Atemwege, insbesondere der Lungen, Infekte des Magen-Darmtraktes, Otitis media, Elektrolytverschiebungen, in letzter Zeit auch sogenanntes gelbes Fett u.a. können in Zusammenwirken mit den Angaben zur Vorgeschichte in vielen Fällen durch die Annahme einer Bakterien-Enterotoxinvergiftung, die im Säuglingsalter anders verläuft als beim grösseren Kind oder Erwachsenen, auf einen gemeinsamen Ursprung zurückgeführt werden.</p><p>Ausführliche Ermittlungen vor der Obduktion, die in gleicher Art und Weise durchgeführte Leichenöffnung sowie der sich daran anschliessender Untersuchungen sind für die Klärung der Ursache des plötzlichen Todes unabdingbare Voraussetzunge, schon damit die Ergebnisse nicht der Bedeutung, die der Obduzent einer bestimmten Untersuchungsmethode beimisst, entsprechen.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 3","pages":"Pages 171-174"},"PeriodicalIF":0.0,"publicationDate":"1978-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80052-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11883047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1978-05-01DOI: 10.1016/S0379-0738(78)80053-X
Bozena Turowska, Maciej Bogusz
The authors describe a Polish family (three generations) with a silent gene Po of human red cell acid phosphatase. The phosphatase levels of 4 family members were about half the normal value.
{"title":"The rare silent gene Po of human red cell acid phosphatase in a second family in Poland","authors":"Bozena Turowska, Maciej Bogusz","doi":"10.1016/S0379-0738(78)80053-X","DOIUrl":"10.1016/S0379-0738(78)80053-X","url":null,"abstract":"<div><p>The authors describe a Polish family (three generations) with a silent gene P<sup>o</sup> of human red cell acid phosphatase. The phosphatase levels of 4 family members were about half the normal value.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 3","pages":"Pages 175-176"},"PeriodicalIF":0.0,"publicationDate":"1978-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80053-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11883048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1978-05-01DOI: 10.1016/S0379-0738(78)80056-5
Z. Mobarah (Alexander von Humboldt Fellow) , D. Bieniek , F. Korte
Analysis of Cannabis sativa L. grown 1300 meters above sea level shows that the amount of propyl cannabinoids is higher than the respective pentyl homologues. High percentages of pentyl and propyl cannabichromenes were produced under these growing conditions.
{"title":"Some chromatographic aspects of hashish analysis. II","authors":"Z. Mobarah (Alexander von Humboldt Fellow) , D. Bieniek , F. Korte","doi":"10.1016/S0379-0738(78)80056-5","DOIUrl":"https://doi.org/10.1016/S0379-0738(78)80056-5","url":null,"abstract":"<div><p>Analysis of <em>Cannabis sativa</em> L. grown 1300 meters above sea level shows that the amount of propyl cannabinoids is higher than the respective pentyl homologues. High percentages of pentyl and propyl cannabichromenes were produced under these growing conditions.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 3","pages":"Pages 189-193"},"PeriodicalIF":0.0,"publicationDate":"1978-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80056-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91777201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1978-05-01DOI: 10.1016/S0379-0738(78)80055-3
S.D. Ferrara, L. Tedeschi, F. Castagna, M. Marigo
The enzyme-multiplied immunoassay technique (EMIT) was compared with the gas-liquid chromatographic (GLC) method in the analysis of 130 urine samples from subjects receiving methadone treatment and non-methadone controls. The GC method allowed the quantitation of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, the major metabolite of methadone. A good correlation was found between the two methods. The advantages of using the EMIT system are discussed.
{"title":"Comparison of GLC-EMIT analysis for the assay of methadone and its major metabolite in urine","authors":"S.D. Ferrara, L. Tedeschi, F. Castagna, M. Marigo","doi":"10.1016/S0379-0738(78)80055-3","DOIUrl":"10.1016/S0379-0738(78)80055-3","url":null,"abstract":"<div><p>The enzyme-multiplied immunoassay technique (EMIT) was compared with the gas-liquid chromatographic (GLC) method in the analysis of 130 urine samples from subjects receiving methadone treatment and non-methadone controls. The GC method allowed the quantitation of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, the major metabolite of methadone. A good correlation was found between the two methods. The advantages of using the EMIT system are discussed.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 3","pages":"Pages 181-188"},"PeriodicalIF":0.0,"publicationDate":"1978-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80055-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11883054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1978-05-01DOI: 10.1016/S0379-0738(78)80058-9
Michael Jastremski, David Powner, James Snyder, Jan Smith, Ake Grenvik
During the last decade there has been philosophical acceptance of the concept that the state of brain death is equivalent to total patient death. The application of this concept to clinical medicine has been associated with major problems in both the diagnosis of brain death and the medical management of the brain dead patient. In our experience with 176 consecutive cases of suspected brain death over a seven-year period, we have found that a standardized protocol applied by experienced clinicians will minimize these problems.
{"title":"Problems in brain death determination","authors":"Michael Jastremski, David Powner, James Snyder, Jan Smith, Ake Grenvik","doi":"10.1016/S0379-0738(78)80058-9","DOIUrl":"10.1016/S0379-0738(78)80058-9","url":null,"abstract":"<div><p>During the last decade there has been philosophical acceptance of the concept that the state of brain death is equivalent to total patient death. The application of this concept to clinical medicine has been associated with major problems in both the diagnosis of brain death and the medical management of the brain dead patient. In our experience with 176 consecutive cases of suspected brain death over a seven-year period, we have found that a standardized protocol applied by experienced clinicians will minimize these problems.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 3","pages":"Pages 201-212"},"PeriodicalIF":0.0,"publicationDate":"1978-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80058-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11883051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1978-05-01DOI: 10.1016/S0379-0738(78)80057-7
D.J. Reuland, W.A. Trinler
An unequivocal determination of heroin in simulated street samples is deseribed. Heroin is separated from the active excipients and contaminants by reverse-phase high-performance liquid chromatography. An infrared spectrum is obtained using semimicro-sampling techniques on the heroin fraction collected. The total analysis time is 50 minutes.
{"title":"An unequivocal determination of heroin in simulated street drugs by a combination of high-performance liquid chromatography and infrared spectrophotometry using micro-sampling techniques","authors":"D.J. Reuland, W.A. Trinler","doi":"10.1016/S0379-0738(78)80057-7","DOIUrl":"https://doi.org/10.1016/S0379-0738(78)80057-7","url":null,"abstract":"<div><p>An unequivocal determination of heroin in simulated street samples is deseribed. Heroin is separated from the active excipients and contaminants by reverse-phase high-performance liquid chromatography. An infrared spectrum is obtained using semimicro-sampling techniques on the heroin fraction collected. The total analysis time is 50 minutes.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 3","pages":"Pages 195-200"},"PeriodicalIF":0.0,"publicationDate":"1978-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80057-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91686601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1978-05-01DOI: 10.1016/S0379-0738(78)80054-1
A. Noirfalise
Two cases of chloroquine intoxication are reported. Chloroquine concentrations in blood and in various tissues, determined by spectrophotometry and thin-layer chromatography, are discussed in the light of existing literature.
报告氯喹中毒2例。用分光光度法和薄层色谱法测定血液和各种组织中的氯喹浓度,根据现有文献进行了讨论。
{"title":"Chloroquine intoxication: Two case reports","authors":"A. Noirfalise","doi":"10.1016/S0379-0738(78)80054-1","DOIUrl":"10.1016/S0379-0738(78)80054-1","url":null,"abstract":"<div><p>Two cases of chloroquine intoxication are reported. Chloroquine concentrations in blood and in various tissues, determined by spectrophotometry and thin-layer chromatography, are discussed in the light of existing literature.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 3","pages":"Pages 177-179"},"PeriodicalIF":0.0,"publicationDate":"1978-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80054-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11883049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}