S. Ramya, D. Lingaraja, G. Ram, S. Kumar, T. Aravind
{"title":"Microfluidic Circulating Tumour Cell Sorter Using Deterministic Lateral Displacement","authors":"S. Ramya, D. Lingaraja, G. Ram, S. Kumar, T. Aravind","doi":"10.1109/DISCOVER52564.2021.9663577","DOIUrl":null,"url":null,"abstract":"This paper presents the separation of rare circulating tumour cells (CTCs) in the range of $15-30\\mu \\text{m}$ by designing the novel microfluidic channel to prognose the level of cancer. Prognosing the level of CTCs in a patient's blood sample will greatly reduce the mortality rate. The developed microchannel structure utilizes the concept of deterministic lateral lateral displacement. Inclusion of arrays of triangular posts with critical diameter of $42\\mu \\text{m}$ improves the separation efficiency. The optimistic microchannel’s efficiency is analyzed by validating critical diameter. Further particle tracing is employed and improved the device throughput.","PeriodicalId":413789,"journal":{"name":"2021 IEEE International Conference on Distributed Computing, VLSI, Electrical Circuits and Robotics (DISCOVER)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2021 IEEE International Conference on Distributed Computing, VLSI, Electrical Circuits and Robotics (DISCOVER)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/DISCOVER52564.2021.9663577","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
This paper presents the separation of rare circulating tumour cells (CTCs) in the range of $15-30\mu \text{m}$ by designing the novel microfluidic channel to prognose the level of cancer. Prognosing the level of CTCs in a patient's blood sample will greatly reduce the mortality rate. The developed microchannel structure utilizes the concept of deterministic lateral lateral displacement. Inclusion of arrays of triangular posts with critical diameter of $42\mu \text{m}$ improves the separation efficiency. The optimistic microchannel’s efficiency is analyzed by validating critical diameter. Further particle tracing is employed and improved the device throughput.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
