Transcatheter aortic valve implantation. Role of imaging

M. Gessat, T. Frauenfelder, L. Altwegg, J. Grünenfelder, V. Falk
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引用次数: 7

Abstract

Transcatheter aortic valve implantation (T-AVI) has shown good results in high-risk patients with severe aortic stenosis. Throughout the whole process of T-AVI, different imaging modalities are indispensable. Preoperatively, multislice computed tomography, angiography and transesophageal echo (TEE) are utilized for patient selection, valve selection, approach selection and the planning of implant placement. Intraoperatively, angiography and TEE are used for controlling placement of the guidewire and valve positioning. Quality control and follow-up require TEE imaging and can require additional CT or angiography studies. In the first half of this paper, we discuss the applicability of different imaging modalities for T-AVI in the light of the current best practice. In the second half of this paper, we present an overview on research projects in medical engineering which aim at development of image-based methods for increasing patient safety during T-AVI. Template-based implantation planning, as it is applied in dental, orthopedic and other surgical disciplines, is proposed as an aid during implant selection in order to help reduce the incidence of complications such as atrioventricular node block and paravalvular leaks. Current research tries to apply state-of-the-art engineering techniques, such as computational fluid dynamics to optimize valve selection and positioning. For intraoperative assistance during valve positioning, real-time image processing methods are proposed to track target landmarks and the stented valve.
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经导管主动脉瓣植入术。成像的作用
经导管主动脉瓣植入术(T-AVI)治疗严重主动脉瓣狭窄的高危患者效果良好。在T-AVI的整个过程中,不同的成像方式是不可或缺的。术前利用多层计算机断层扫描、血管造影和经食管回声(TEE)进行患者选择、瓣膜选择、入路选择和种植体放置计划。术中,血管造影和TEE用于控制导丝的放置和瓣膜的定位。质量控制和随访需要TEE成像,并可能需要额外的CT或血管造影研究。在本文的前半部分,我们根据目前的最佳实践讨论了不同成像方式对T-AVI的适用性。在本文的后半部分,我们概述了医学工程中的研究项目,旨在开发基于图像的方法,以提高T-AVI期间的患者安全。基于模板的植入计划应用于牙科、骨科等外科学科,可作为选择植入物的辅助手段,以减少房室结阻滞、瓣旁漏等并发症的发生。目前的研究试图应用最先进的工程技术,如计算流体动力学来优化阀门的选择和定位。为了在术中辅助瓣膜定位,提出了实时图像处理方法来跟踪目标地标和支架瓣膜。
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