S. Hafizovic, F. Heer, U. Frey, T. Ugniwenko, A. Blau, C. Ziegler, A. Hierlemann
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引用次数: 5
Abstract
We report on a complementary-metal-oxide-semiconductor-based system that is capable of bidirectionally communicating (stimulation and recording) with electrogenic cells such as neurons or cardiomyocytes. It is is targeted at investigating electrical signal propagation within cellular networks in vitro. Experiments including the stimulation of neurons with two different spatio-temporal patterns and the recording of the triggered spiking activity have been carried out. The neuronal response patterns have been successfully classified (83% correct classifications) with respect to the different stimulation patterns. It will be demonstrated that information processing using natural neuronal networks may be possible
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