Assessment of serum ferritn level in detection of iron deficiency anaemia in paediatric patients: Prospective analysis

Dr. Patel Riya Biponbhai, Dr. Pragya Khanna
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Abstract

Introduction: Major form in which iron is stored in the body is serum ferritin. It can detect early changes in body iron store. It causes little patient discomfort as compared to bone marrow iron studies. In this study, we used serum ferritin level to assess the level of iron storage in the children less than five years of age. Iron stores are depleted below this value. Materials & Methods: Sample size includes 100 children under the age of 5 years from the opd of the department. The blood was divided into two halves, one was sent for cbc evaluation and from other half the serum was separated through centrifugation for the estimation of serum ferritin level. Results: The range of the serum iron level in the study was 0.2 – 340 ng/ml. The mean serum iron level in the study was 51.8 ng/ml. Out of 100 patients, there were 76 patients with serum level less than 12 ng/ml; they were iron deficient. There were 20 children with iron deficiency in the infants group, there were 34 patients in toddlers group and there were 24 children in preschool group. Discussion & Conclusion: For the early detection of the status of the iron stores in the body is done by serum ferritin concentration. Iron deficiency anemia continues to be a significant public health problem in the world. Serum ferritin level is a good screening test for early detection of iron deficiency anemia in children less than 5 years of age. When it is used in assess with other test for iron status in body, it is considered as more specific indicator for the detection of the iron stores.
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评估血清铁蛋白水平检测缺铁性贫血的儿科患者:前瞻性分析
铁在体内储存的主要形式是血清铁蛋白。它可以检测体内铁含量的早期变化。与骨髓铁研究相比,它几乎不会引起患者不适。在这项研究中,我们使用血清铁蛋白水平来评估5岁以下儿童的铁储存水平。铁储量低于这个值就会耗尽。材料与方法:样本量为本科门诊5岁以下儿童100例。血液被分成两半,一部分送去做cbc评估,另一部分通过离心分离血清用于估计血清铁蛋白水平。结果:本研究血清铁水平范围为0.2 ~ 340 ng/ml。研究中平均血清铁水平为51.8 ng/ml。100例患者中,76例患者血清水平低于12 ng/ml;他们缺铁。婴儿组缺铁20例,幼儿组缺铁34例,学龄前缺铁24例。讨论与结论:通过测定血清铁蛋白浓度可早期检测机体铁储备状态。缺铁性贫血仍然是世界上一个重大的公共卫生问题。血清铁蛋白水平是早期发现5岁以下儿童缺铁性贫血的良好筛查试验。当它与其他铁在体内状态的检测一起评估时,被认为是检测铁储量的更具体的指标。
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