Causal Structure Learning with Reduced Partial Correlation Thresholding

A. Sondhi, A. Shojaie
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Abstract

Directed acyclic graphs (DAGs) are commonly used to represent causal relations within a large number of random variables. Estimating DAGs from observational data is a difficult task, it is often impossible to uniquely determine edge direction. The skeleton of the graph, where directions are removed from edges, is often estimated instead. We consider the task of estimating the skeleton of a potentially high-dimensional DAG consisting of Gaussian random variables. A drawback of existing methods is that a prohibitively large number of conditional independence relations need to be tested for. By exploiting properties of common random graph families, we develop a new algorithm that requires conditioning only on small sets of variables. By extending previous theoretical results for undirected graphs to the setting of directed graphs, we prove the consistency of our algorithm, and demonstrate improvements over the state-of-the-art alternative in low and high-dimensional simulation settings. We conclude by applying our proposed algorithm on a real gene expression data set.
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有向无环图(dag)通常用于表示大量随机变量之间的因果关系。从观测数据估计dag是一项困难的任务,通常不可能唯一地确定边缘方向。图的骨架,即从边缘上去除方向,通常是估计的。我们考虑估计由高斯随机变量组成的潜在高维DAG的骨架的任务。现有方法的一个缺点是需要测试大量的条件独立关系。通过利用常见的随机图族的性质,我们开发了一种新的算法,它只需要对小的变量集进行调节。通过将先前无向图的理论结果扩展到有向图的设置,我们证明了算法的一致性,并证明了在低维和高维模拟设置中优于最先进的替代方案的改进。最后,我们将提出的算法应用于真实的基因表达数据集。
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