Histopathological Changes in the Kidney of the Freshwater Bronze Featherback Fish, Notopterus notopterus (Pallas, 1769) Exposed to Profenofos

S. Tazeen, R. Kulkarni
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Abstract

The impact of profenofos, an organophosphate pesticide on the kidney of Indian freshwater teleost fish Notopterus notopterus was evaluated. The experimental group was exposed to sublethal concentration of profenofos at 7, 14 and 21 days. Histopathological changes due to the toxicity of pesticide in experimental and control kidney of the fish were observed by killing the animal every 7, 14 and 21 days. The kidneys were fixed in Bouin’s solution, dehydrated in graded ethanol, infiltrated in xylene, sectioned at 4-6 µ and stained in haematoxylin and eosin. Haemorrhage, oedema, fragmented glomeruli and elongated kidney tubules in experimental fish, and no effect were however observed in control fishes. It is concluded that profenofos is significantly toxic to the fish.
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淡水青铜羽背鱼Notopterus Notopterus (Pallas, 1769)肾脏的组织病理学变化
研究了有机磷农药丙诺福斯对印度淡水硬骨鱼Notopterus Notopterus肾脏的影响。实验组分别于第7、14、21天分别暴露于亚致死浓度的丙诺威。分别于7、14、21 d杀鱼,观察实验和对照肾因农药毒性引起的组织病理学变化。将肾脏固定在Bouin溶液中,用分级乙醇脱水,二甲苯浸润,在4-6µ处切片,并用血红素和伊红染色。实验鱼出现出血、水肿、肾小球碎裂和肾小管拉长,而对照鱼则没有观察到任何影响。结论是,丙诺威对鱼类有显著毒性。
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