The Germinal Triumvirate- Wilm’s Tumour

Abstract

Additionally, designated as nephroblastoma, tri-phasic embryonal Wilma’s tumour is constituted of varying quantities of blastemal, epithelial and stromal components. Besides, biphasic and monophasic neoplasms are frequently discerned. Epithelial and stromal elements may emerge as poorly differentiated to well differentiated components. Morphological assessment of tri-phasic Wilm’s tumour is efficacious and confirmatory. However, appropriate categorization of neoplasms composed of pure blastema, epithelium or stroma can be challenging. Extensive tissue sampling, pertinent immunohistochemistry and molecular techniques are advantageously adopted in discerning cogent diagnostic features.