{"title":"Research Progress of Crispr / Cas9 System in Hematological Diseases and Cancer","authors":"Jingxuan Wu","doi":"10.1145/3570773.3570830","DOIUrl":null,"url":null,"abstract":"In recent years, gene editing technology has made great breakthroughs in the treatment of various genetic diseases by knockout, mutation, replacement or addition of DNA. Based on this system, scientists developed a new genome editing technology—CRISPR / Cas9 technology. CRISPR / Cas9 technology has shown great potential in the treatment of many diseases, bringing new possibilities for the treatment of many diseases. Compared with many traditional therapies, the CRISPR / Cas9 system has higher precision, simpler and more convenient operation, and less chance of off-target effects. This paper mainly introduces the basic principle of the CRISPR / Cas9 system and its application in hematological diseases and cancer, aiming to further promote the application of the CRISPR / Cas9 system in clinical diseases.","PeriodicalId":153475,"journal":{"name":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1145/3570773.3570830","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, gene editing technology has made great breakthroughs in the treatment of various genetic diseases by knockout, mutation, replacement or addition of DNA. Based on this system, scientists developed a new genome editing technology—CRISPR / Cas9 technology. CRISPR / Cas9 technology has shown great potential in the treatment of many diseases, bringing new possibilities for the treatment of many diseases. Compared with many traditional therapies, the CRISPR / Cas9 system has higher precision, simpler and more convenient operation, and less chance of off-target effects. This paper mainly introduces the basic principle of the CRISPR / Cas9 system and its application in hematological diseases and cancer, aiming to further promote the application of the CRISPR / Cas9 system in clinical diseases.
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