Initial validation of a brief assessment of cannabis demand among young adult college students

Benjamin L Berey, E. Aston, Ricarda K Pritschmann, C. Murphy, Ali M. Yurasek
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引用次数: 1

Abstract

Behavioral economic models of addiction posit that cannabis’s reinforcing value (demand) is linked to use. The Marijuana Purchase Task (MPT; Aston et al., 2015) quantifies demand by assessing hypothetical cannabis consumption across escalating price points. Indices generated from MPT performance include intensity (i.e., amount consumed when free), Omax (i.e., peak expenditure), Pmax (i.e., price at peak expenditure), elasticity (i.e., degree that consumption decreases as price increases), and breakpoint (i.e., cost suppressing consumption to zero). Cannabis demand is linked to engagement in risky behaviors and cannabis use disorder (CUD) symptomology. However, the length of the MPT makes repeated assessment of state-dependent changes in cannabis demand difficult, which limits clinical utility. Brief assessments of alcohol and cigarette demand exist that measure intensity, Omax, and breakpoint. Thus, the aim of the current study was to develop and validate a brief assessment of cannabis demand. College students (N=211, Mage=19.91, SD=1.44; 63% Female; 56.4% Non-Hispanic Caucasian) who reported past-month cannabis use ≥3 times completed an online survey. Participants completed the MPT, a 3-item brief assessment of marijuana demand (BAMD) assessing intensity, Omax, and breakpoint, and measures of demographics, cannabis use frequency, cannabis-related negative consequences, CUD symptomology based on DSM-5 criteria, and cannabis craving. Convergent validity was examined via bivariate correlations of demand indices on the BAMD, MPT, and cannabis outcome measures. Divergent validity was assessed via independent samples t-tests to examine whether demand indices on the BAMD differed based on the presentation or absence of CUD. A one-way between-subjects ANOVA with planned comparisons was tested to compare effects of CUD severity (mild/moderate/severe) on BAMD demand indices. Intensity, Omax, and breakpoint were significantly correlated across the MPT and BAMD (rs=.30 – .79, ps<.01). Intensity, Omax, and breakpoint on the MPT and BAMD were significantly correlated with current cannabis craving, CUD severity, and cannabis-related negative consequences (rs=.18 – .48, ps<.05). Only intensity and Omax were significantly correlated with cannabis use (rs=.16 – .43, ps<.01). Individuals with (versus without) a CUD reported significantly greater intensity and Omax (ps< .01), but not breakpoint, on the MPT and BAMD. There were significant effects of CUD severity on B-MPT demand indices (ps<.05). Planned comparisons revealed that individuals with a moderate or severe CUD had significantly elevated intensity, Omax, and breakpoint on the BAMD compared to individuals with a mild CUD. Only breakpoint differentiated individuals with a moderate and severe CUD. This is the first study to validate a brief assessment of cannabis demand. Consistent with prior alcohol and tobacco research, the BAMD espoused convergent validity with the MPT and divergent validity by differentiating individuals with and without a CUD and along the CUD severity continuum. Thus, the BAMD may be a useful tool to assess links between specific indices of cannabis demand and clinically-relevant outcomes over time and in real-world settings. However, given the rise in novel cannabis products with different modes of administration and varying potencies, future research should examine whether demand differs based on these factors. Further, replicating these findings among more diverse populations is essential.
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对青年大学生大麻需求简要评估的初步验证
成瘾的行为经济学模型假设大麻的强化价值(需求)与使用有关。大麻购买任务(MPT);Aston等人,2015)通过评估不断升级的价格点的假设大麻消费来量化需求。由MPT性能生成的指标包括强度(即空闲时的消费量)、Omax(即峰值支出)、Pmax(即峰值支出时的价格)、弹性(即消费随着价格上涨而减少的程度)和断点(即成本将消费抑制到零)。大麻需求与从事危险行为和大麻使用障碍(CUD)症状有关。然而,MPT的长度使得反复评估大麻需求的州依赖变化变得困难,这限制了临床效用。对酒精和香烟需求的简要评估可以测量强度、极限和断点。因此,本研究的目的是制定和验证对大麻需求的简要评估。大学生(N=211, Mage=19.91, SD=1.44;63%的女性;56.4%非西班牙裔白人)报告过去一个月使用大麻≥3次完成了在线调查。参与者完成了MPT,大麻需求的3项简短评估(BAMD)评估强度,Omax和断点,以及人口统计,大麻使用频率,大麻相关负面后果,基于DSM-5标准的CUD症状和大麻渴望的测量。通过bmd、MPT和大麻结果测量的需求指数的双变量相关性来检验收敛效度。通过独立样本t检验评估分歧效度,以检验bmd的需求指数是否因出现或不存在CUD而不同。采用计划比较的单向受试者间方差分析比较CUD严重程度(轻度/中度/严重)对bmd需求指数的影响。强度、Omax和断点在MPT和BAMD之间显著相关(rs=。30 - 0.79, ps< 0.01)。MPT和BAMD的强度、Omax和断点与当前的大麻渴望、CUD严重程度和大麻相关的负面后果显著相关(rs=。18 - 0.48, ps< 0.05)。只有强度和Omax与大麻使用显著相关(rs=。16 - 0.43, ps< 0.01)。有(与没有)CUD的个体在MPT和BAMD上报告的强度和Omax显著增加(ps< 0.01),但没有断点。CUD严重程度对B-MPT需求指数有显著影响(ps< 0.05)。计划比较显示,与轻度CUD患者相比,中度或重度CUD患者的BAMD强度、Omax和断点显著升高。只有断点区分中度和重度CUD个体。这是第一个验证大麻需求简要评估的研究。与先前的酒精和烟草研究一致,BAMD通过区分患有和没有CUD的个体以及CUD严重程度连续体,支持与MPT的趋同效度和发散效度。因此,BAMD可能是一个有用的工具,可以评估大麻需求的具体指数与临床相关结果之间的联系,随着时间的推移和现实世界的设置。然而,鉴于具有不同给药模式和不同效力的新型大麻产品的增加,未来的研究应检查需求是否基于这些因素而有所不同。此外,在更多样化的人群中复制这些发现是必不可少的。
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