Yeni Koronavirüs Hastalığının (Covid-19) Klinik, Laboratuvar ve Radyolojik Sonuçlarının İncelenmesi

M. Kaya, M. Demirkol
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Abstract

Covid-19, which emerged in China in December 2019 and spread to the whole world in a short time, has been a serious public health problem threatening humanity. In this study, we aimed to reveal demographic, clinical, laboratory and radiological features of patients diagnosed with Covid-19. The study is a retrospective cross-sectional study consisting of patients who were hospitalized in health institutions in Bolu, Turkey between 11.03.2020 and 19.04.2020 with a definitive or probable diagnosis of Covid-19. The number of patients in the study was 262. The mean age of the patients participating in the study was 57.39 ± 19.85, the youngest patient was 19 and the oldest was 94 years old. Of the patients, 40.1% was between the ages of 18-50, 59.9% were over 50 years old. 55.3% of the patients were women and 44.7% were men. Most common symptoms were fever (75.6%), cough (71.8%) and dyspnea (46.9%). Elevated CRP (in 71.3%), elevated LDH (in 56.9%), elevated D-DIMER (in 56.4%) and lymphopenia (in 30.5) were most detected laboratory abnormalities. The result of the real-time reverse-transcription polymerase chain reaction (RT-PCR) test was positive in 35.5% of 262 patients. 88.5% of the patients had chest CT findings compatible with Covid-19. Additionally, 24% had both positive RT-PCR results and CT findings compatible with Covid-19. Expected findings were found to be in older patients more than younger ones. We suggest that clinical features, laboratory abnormalities and radiological findings can be used to provide an early diagnosis and treatment of Covid-19.
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新冠肺炎疫情于2019年12月在中国首次出现,并在短时间内蔓延至全球,已成为威胁人类的严重公共卫生问题。在这项研究中,我们旨在揭示新冠肺炎患者的人口学、临床、实验室和放射学特征。该研究是一项回顾性横断面研究,包括2020年3月11日至2020年4月19日期间在土耳其Bolu卫生机构住院的确诊或可能诊断为Covid-19的患者。该研究的患者人数为262人。参与研究的患者平均年龄57.39±19.85岁,年龄最小19岁,年龄最大94岁。年龄在18-50岁之间的占40.1%,50岁以上的占59.9%。女性占55.3%,男性占44.7%。最常见的症状是发热(75.6%)、咳嗽(71.8%)和呼吸困难(46.9%)。CRP升高(71.3%)、LDH升高(56.9%)、d -二聚体升高(56.4%)和淋巴细胞减少(30.5%)是最常见的实验室异常。262例患者实时反转录聚合酶链反应(RT-PCR)检测结果为阳性,阳性率为35.5%。88.5%的患者胸部CT表现与新冠肺炎相符。此外,24%的人的RT-PCR结果和CT结果都与Covid-19相符。预期的结果在老年患者中比在年轻患者中更常见。我们建议结合临床特征、实验室异常和影像学表现,早期诊断和治疗新冠肺炎。
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