Current information of H9N2 virus zoonotic infection and its emerging pandemic potential: A review

Mohit Kamthania, R. Kumari, Sirajuddin Ali, A. Hussain, A. Jha
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Abstract

H9N2 avian influenza viruses cause worldwide infections in animals including humans and show a threat as a pandemic infection. Since 1998 more than 59 cases including one death due to H9N2 infection had been reported worldwide and the majority of confirmed cases were young children. Due to the large host variety, tolerance to both poultry and mammals and widespread gene reassortment, H9N2 viruses played a crucial role in worldwide infection. In this review, we discuss the current worldwide infection of H9N2 avian influenza viruses as well as their host range, pathogenesis, epidemiology, diagnosis, control, and its pandemic potential.
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H9N2病毒人畜共患感染的最新信息及其新出现的大流行潜力:综述
H9N2禽流感病毒在世界范围内引起包括人类在内的动物感染,并显示出大流行感染的威胁。自1998年以来,全世界报告了59例以上的H9N2感染病例,其中包括一例死亡病例,大多数确诊病例为幼儿。由于宿主种类繁多,对家禽和哺乳动物的耐受性以及广泛的基因重组,H9N2病毒在全球感染中起着至关重要的作用。本文综述了目前世界范围内H9N2禽流感病毒的感染情况、宿主范围、发病机制、流行病学、诊断、控制及其大流行潜力。
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