Advancements in Diagnosis and Treatment of Influenza virus

Huma Amjad, Fahim Ahmed, I. Ullah, M. Rehman
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Abstract

Flu is caused by influenza A and B virus leading an acute respiratory illness. This review summarizes advance diagnostic techniques for detecting and confirming influenza virus and treatments involve. RADTS are beneficial tools but with the limited sensitivity. Pandemic confirmation H1N1 influenza A infection done by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR) or viral culture. Several approaches are as of now accessible for determination of flu contaminations like serological tests are generally used to identify flu infection in immunizer reactions incorporate hemagglutination restraint test that depends on capacity of HA-explicit antibodies. Rapid molecular assays that produces results in approximately in 15-30minutes by detecting nucleic acids of influenza in upper respiratory tract. For treating influenza antiviral medications are given to patients based on clinical and epidemiological factors. Neuraminidase inhibitor (NI) is the drug of choice. A good way to prevent the disease is to give individuals annual vaccine and another way is to start an early diagnosis and give medications in short time to patients to prevent further spread of disease and reduce complications otherwise.
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流感病毒的诊断和治疗进展
流感是由甲型流感和乙型流感病毒引起的急性呼吸道疾病。本文综述了流感病毒检测和确认的最新诊断技术及其治疗方法。RADTS是一种有益的工具,但灵敏度有限。通过实时逆转录聚合酶链反应(rRT-PCR)或病毒培养方法确认H1N1甲型流感大流行感染。到目前为止,有几种方法可用于确定流感污染,如血清学测试,通常用于确定流感感染的免疫反应,包括血凝抑制测试,这取决于ha显式抗体的能力。快速分子测定法通过检测上呼吸道流感的核酸,大约在15-30分钟内产生结果。在治疗流感时,根据临床和流行病学因素给予患者抗病毒药物。神经氨酸酶抑制剂(NI)是首选药物。预防这种疾病的一个好方法是每年给个人接种疫苗,另一种方法是开始早期诊断,并在短时间内给病人服用药物,以防止疾病进一步传播,减少并发症。
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