Review of the efficacy and safety of SGLT2 inhibitors in heart failure patients with low left ventricular ejection fraction without diabetes mellitus

E. V. Lomakin
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Abstract

Heart failure (HF) with low left ventricular ejection fraction (LVEF) is a disease with an unfavorable prognosis, for the treatment of which there is a need to search for drugs that improve patients’ quality of life. Such a group of drugs is inhibitors of sodium-glucose cotransporter type 2 (iSGLT-2). Purpose of the study: to assess the efficacy and safety of the new class of antihyperglycemic drugs — iSGLT-2.
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SGLT2抑制剂治疗无糖尿病低左室射血分数心衰患者的疗效和安全性综述
心力衰竭(HF)合并低左心室射血分数(LVEF)是一种预后不良的疾病,其治疗需要寻找能够改善患者生活质量的药物。这组药物是钠-葡萄糖共转运蛋白2型(iSGLT-2)的抑制剂。研究目的:评价一类新型降糖药物- iSGLT-2的有效性和安全性。
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