Prediction and Key Characteristics of All-Cause Mortality in Maintenance Hemodialysis Patients

Mu Xiangwei, Zhuang Mingjie, Liu Shuxin, Li Kequan, You Lianlian, Che Shuang
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Abstract

Predict and analyze key features of all-cause death in maintenance hemodialysis patients to provide guidance for later diagnosis and treatment. Four machine learning methods were used to establish an all-cause death prediction model for maintenance hemodialysis patients and compare their performance. Analyze the key characteristics that have an important impact on all-cause death, and conduct user portraits for patients of different ages and genders. After comparison, the random forest algorithm works best, and an important factor affecting the all-cause death of patients is obtained. Among them, the all-cause death of all patients is related to factors such as albumin, blood potassium, blood magnesium, and urea; With age, the importance of factors such as blood sodium and phosphorus increases, and the importance of factors such as cardiac ultrasound ejection fraction decreases. Finally, there were also differences in the importance of analyzing patients of different ages and different sexes affecting their all-cause death. It is useful for residents to adjust their dialysis index timely.
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维持性血液透析患者全因死亡率的预测及关键特征
预测和分析维持性血液透析患者全因死亡的关键特征,为后期诊断和治疗提供指导。采用4种机器学习方法建立维持性血液透析患者全因死亡预测模型,并对其性能进行比较。分析对全因死亡有重要影响的关键特征,对不同年龄和性别的患者进行用户画像。经过比较,随机森林算法效果最好,得到了影响患者全因死亡的重要因素。其中,所有患者的全因死亡均与白蛋白、血钾、血镁、尿素等因素有关;随着年龄的增长,血钠、磷等因素的重要性增加,心脏超声射血分数等因素的重要性降低。最后,分析不同年龄、不同性别患者对其全因死亡影响的重要性也存在差异。及时调整居民的透析指标是有益的。
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