Algorithm to Avoid Normal Tissue Sacrifice and Thermal Injury of Neighbouring Organs During Radiofrequency Ablation of HCC Tumours Treated Using a Multi-Tine Electrode With Separately Controlled Tines

M. Dhiman, R. Repaka
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Abstract

Radiofrequency ablation of Hepatocellular Carcinomas lacks electrode level feature to (a) avoid the risk of thermal injury to the neighbouring organs and (b) avoid the sacrifice of normal hepatic tissue. The absence of such a feature causes additional intrusion of the human body to overcome the first problem, while there is no solution for the latter problem. An algorithm has been developed and implemented using an unconventional multi-tine RFA electrode to incur ablations specific to the shape and position of target tumours to solve these problems. Further, this algorithm can suggest the best insertion angle for the trocar, such that minimum normal tissue is sacrificed. This suggestion is made quickly with the help of a pre-simulated database. For verification of the algorithm, pre-segmented tumours have been used as inputs and damages incurred with and without algorithm have been compared.
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不同控制时间的多时间电极射频消融治疗HCC肿瘤时避免正常组织牺牲和邻近器官热损伤的算法
肝细胞癌的射频消融缺乏电极水平的特征,无法(a)避免邻近器官的热损伤风险,(b)避免正常肝组织的牺牲。如果没有这一特征,就会对人体造成额外的侵入,以克服第一个问题,而后一个问题则没有解决方案。为了解决这些问题,研究人员开发并实施了一种算法,该算法使用一种非常规的多次射频消融电极,根据目标肿瘤的形状和位置进行消融。此外,该算法还可以建议套管针的最佳插入角度,从而使正常组织损失最小。在预模拟数据库的帮助下,这个建议很快就得到了。为了验证算法,使用预分割的肿瘤作为输入,并比较了使用和不使用算法所造成的损害。
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