Inherited and Acquired Thrombophilia and Infertility

A. Soligo, R. Barini
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Abstract

Implantation failure persists as an important challenge in Human Reproduction. Besides, it is useful to avoid adds on for these patients without scientific evidence. The thrombophilic factors play a role in those situation, but the evidence remain uncertainly. Our researches suggest that protein C and anticardiolipin antibody are more frequently in infertile women. Investigation of acquired and inherited thrombophilia should be considered, particularly in recurrent implantation failure. However, prospective population studies are needed to confirm the data presented.
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遗传性和获得性血栓病和不孕症
着床失败一直是人类生殖的重要挑战。此外,在没有科学证据的情况下,避免对这些患者进行添加是有用的。血栓形成因子在这些情况下起作用,但证据仍然不确定。我们的研究表明,蛋白C和抗心磷脂抗体在不孕症妇女中更常见。应考虑对获得性和遗传性血栓性疾病的调查,特别是在反复植入失败的情况下。然而,需要前瞻性的人口研究来证实所提出的数据。
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