{"title":"Structural and functional analysis of ribosome subunits isolated from mouse liver following a toxic dose of dimethylnitrosamine.","authors":"A Delpino, U Ferrini","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Ribosomal subunits, isolated from mouse liver after a single dose of 50 mg/Kg b. w. of DMN, have been tested for their structural and functional properties. CsCl analysis has shown that after DMN treatment no loss of structural proteins occurs in both 40 S and 60 S ribosome subunits. It has been also demonstrated that these subunits are able to synthetize in the poly-U programmed system at low Mg++ concentrations, in the presence of heterologous initiation factors, at the same efficiency as the corresponding controls.</p>","PeriodicalId":8354,"journal":{"name":"Archivio di scienze biologiche","volume":"60 1-4","pages":"49-58"},"PeriodicalIF":0.0000,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivio di scienze biologiche","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Ribosomal subunits, isolated from mouse liver after a single dose of 50 mg/Kg b. w. of DMN, have been tested for their structural and functional properties. CsCl analysis has shown that after DMN treatment no loss of structural proteins occurs in both 40 S and 60 S ribosome subunits. It has been also demonstrated that these subunits are able to synthetize in the poly-U programmed system at low Mg++ concentrations, in the presence of heterologous initiation factors, at the same efficiency as the corresponding controls.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
