PATHOGENETIC FEATURES OF THE INFLUENCE OF A PAST CORONAVIRUS INFECTION IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME

Abstract

From July 1, 2022, restrictions related to the spread of COVID-19 were lifted in Russia. But until now, according to experts, COVID-19 remains one of the most important medical problems for the global community. In 2023, 11 thousand people died from COVID-19 in the world, about 3 million were infected. There are cases known for complications from other organ systems in patients with COVID-19. However, in the general population, the course of COVID-19 is more severe in people with dyslipidaemia, obesity and hypertension. Often, these comorbidities are associated with polycystic ovary syndrome (PCOS). It is possible that women with PCOS will experience more severe clinical manifestations in the future. For 2020–2023 many women reported experiencing menstrual irregularities for the first time, which raised concerns about the impact of SARS-CoV-2 on reproductive function. There are currently insufficient clinical and statistically significant data to establish the causes of these disorders. This material is devoted to the analysis of the probable causes of menstrual irregularities in women with PCOS after a coronavirus infection: the possible direct effect of SARS-CoV-2 on the organs of the female reproductive system depending on the PCOS phenotype.