Development of a Classifier for the Diagnosis of Oncological Diseases Based on Blood Protein Markers

L. Demidova, A. K. Gornostaev
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Abstract

The article deals with the problem of classifying oncological diseases by blood protein markers. To solve this problem, it is proposed to develop 2 data classifiers based on the SVM algorithm and a fully connected neural network using a three-class dataset containing normal patterns and patterns corresponding to 2 oncological diseases. At the same time, it is proposed to introduce dropout layers into the classifier based on a neural network in order to combat overfitting and use a special method for forming packages used in training to level the problem of class imbalance identified in the analysis of the dataset. The results of experimental studies show the advantage of the neural network-based classifier compared to the SVM classifier, which consists in a higher quality of the classification of minority classes corresponding to 2 oncological diseases.
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基于血液蛋白标记物的肿瘤疾病诊断分类器的研制
本文讨论了用血液蛋白标记物对肿瘤疾病进行分类的问题。为了解决这一问题,我们提出利用包含正常模式和2种肿瘤疾病对应模式的三类数据集,开发基于SVM算法的2个数据分类器和一个全连接神经网络。同时,提出了在基于神经网络的分类器中引入dropout层来对抗过拟合,并使用特殊的方法形成训练中使用的包来解决在数据集分析中识别出的类不平衡问题。实验研究结果表明,基于神经网络的分类器相对于SVM分类器的优势在于对2种肿瘤疾病对应的少数类的分类质量更高。
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