Gebelikten önce COVID-19 geçirenlerde ilk trimester uterine arter direnci, plasental volüm ve gebelik sonuçlarının incelenmesi

M. Özer, Pınar Tuğçe Özer, Alper İleri̇, Sercan Kantarci, H. G. Pala
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Abstract

Aim There are studies showing that acquiring Coronavirus Disease 2019 (COVID-19) while pregnant might cause vascular damage, affect uterine blood circulation, and worsen pregnancy outcomes. In this study, we looked at the first-trimester placental development and pregnancy outcomes in people who conceived after getting better from COVID-19. We also looked into the durability of the COVID-19's effects on pregnancy. Matherials and Methods This prospective case-control study investigates placental volume and uterine artery Doppler flow differences in pregnant women with COVID-19 exposure within a year prior to pregnancy versus healthy pregnant controls. Result In a study involving 50 patients and 50 controls, it was discovered that demographic traits like age, birth rate, and body mass index were comparable. There were statistically insignificant slight differences in these results when different outcomes, including as oligohydramnios, preterm, preeclampsia, and intrauterine growth retardation, were studied. While birth weight revealed similarity between the two groups, placental volume and uterine artery Doppler results did not reveal any appreciable variations. Conclusion No distinction between the groups' placental or Doppler readings was found in the investigation that was completed. This work has helped identify the impacts of COVID-19 contracted prior to pregnancy on gestation, whereas previous study has mainly focused on the impact of COVID-19 infected during pregnancy.
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目的有研究表明,妊娠期感染新冠肺炎(COVID-19)可能导致血管损伤,影响子宫血液循环,使妊娠结局恶化。在这项研究中,我们研究了在COVID-19好转后怀孕的人的妊娠早期胎盘发育和妊娠结局。我们还研究了COVID-19对怀孕影响的持久性。材料与方法本前瞻性病例对照研究调查了妊娠前一年内暴露于COVID-19的孕妇与健康孕妇对照组胎盘体积和子宫动脉多普勒血流的差异。结果在一项涉及50名患者和50名对照组的研究中,发现年龄、出生率和体重指数等人口统计学特征具有可比性。当研究羊水过少、早产、先兆子痫和宫内发育迟缓等不同结局时,这些结果差异无统计学意义。虽然出生体重在两组之间显示相似,但胎盘体积和子宫动脉多普勒结果没有显示任何明显的差异。结论在已完成的调查中,各组胎盘或多普勒读数无明显差异。这项工作有助于确定怀孕前感染的COVID-19对妊娠的影响,而之前的研究主要集中在怀孕期间感染COVID-19的影响。
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